Dr. Bhisham Narayan Singh is an Assistant Professor in the Department of Biotechnology at the Manipal School of Life Sciences (MSLS), Manipal Academy of Higher Education, Manipal, India. He earned his Ph.D. in Tissue Engineering from the National Institute of Technology Rourkela, followed by postdoctoral research at the School of Biochemical Engineering, Indian Institute of Technology–Banaras Hindu University.
Dr. Singh’s research primarily focuses on biomaterials, regenerative medicine, tissue engineering, and biomedicine. As a dedicated researcher in these fields, he leads a team at the Biomaterial and Biomanufacturing Laboratory (BBL), Manipal School of Life Sciences, MAHE, Manipal, working on innovative strategies to repair and regenerate damaged tissues, particularly for orthopaedic applications.
His group is actively engaged in developing solutions for the regeneration of complex tissues, including bone, cartilage, osteochondral tissue, mandibular bone, dura mater, skin, and vascular structures. By integrating a range of fabrication techniques—from traditional scaffold-based methods to cutting-edge 3D bioprinting—his team strives to replicate the native tissue environment and enhance the outcomes of regenerative therapies.

A novel biphasic bioceramic with precisely controlled phase ratios has been developed and evaluated for critical bone defect repair. By fine-tuning synthesis parameters, he has created biomaterials that enhance osteointegration, mechanical stability, and bioactivity—offering solution for orthopedic applications. Additionally, his team are actively researching non-union bone segment regeneration, addressing one of the most challenging aspects of bone healing by developing 3D bioengineered solutions to bridge large defects and restore function. His lab is currently supported by funding through SERB and DBT, Government of India for the development of tissue engineered graft for the treatment of non-union fractures and osteoarthritis. Also, he received funding from ICMR, GOI for the development of bioresorbable small diameter vascular graft. Currently, his team is working on development of indigenous hybrid tissue engineered graft mimicking trilayered structure of blood vessel and its mechanical properties for reconstruction of damaged/diseased vascular tissue.

His work spans the regeneration of bone, cartilage, osteochondral tissue, mandibular bone, dura mater, skin, and vascular structures

10 year of experience

Awards and recognition:

 Awarded with The SICOT Research Award: Best Clinical Research Paper by International Society of Orthopeadics Surgery & Traumatology, Kuala lumpur, 29-09-2022.
 Awarded with Best Poster Presentation in 6th Asian Biomaterial Congress, 2017.
 Received membership from Royal Society of Chemistry for free subscription of Journal of Biomaterial Sciences from 2017 – 2018.