Personal profile
Professional Information
Dr. Dileep Kumar is an Assistant Professor (Senior Scale) at the Manipal College of Pharmaceutical Sciences (MCOPS), Manipal Academy of Higher Education (MAHE), with extensive teaching and research experience in medicinal chemistry and machine learning–driven drug discovery. His academic contributions include mentoring postgraduate research projects, delivering lectures in advanced pharmaceutical chemistry, and publishing scholarly work in reputed Scopus and Web of Science–indexed journals.
Dr. Kumar’s research integrates machine learning and artificial intelligence with traditional medicinal chemistry approaches to accelerate drug discovery and molecular design. His work focuses on AI-guided synthesis of heterocyclic compounds, machine learning–based development of EGFR inhibitors, and computational modeling of GluN2B-selective modulators for neurodegenerative disorders such as Alzheimer’s disease. Through this interdisciplinary approach, he aims to bridge synthetic chemistry with data-driven predictive modeling to advance precision drug design.
Research interests
Dr. Dileep Kumar’s research focuses on the synthesis of heterocyclic compounds, chiral drug impurities, and stable isotope–labeled internal standards. His current work explores deuterated curcuminoids and their potential therapeutic benefits. He is actively involved in the design and development of novel GluN2B-selective negative allosteric modulators for neurodegenerative disorders such as Alzheimer’s disease. Additionally, his group employs artificial intelligence and machine learning–guided approaches for rational drug design, particularly in developing EGFR inhibitors for the treatment of breast cancer.
Experience
7 year
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Applications of functionalized magnetic nanoparticles in cosmetics industry
Viswalingam, V. & Kumar, D., 01-01-2026, Industrial Applications of Functionalized Magnetic Nanoparticles. Elsevier, p. 387-407 21 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Comprehensive chemico-pharmacological profiling of Ailanthus excelsa Roxb bark: An integrated GC-MS/MS and molecular dynamics approach with free energy landscape and PCA insights
Gudasi, S., Gharge, S., Kumar, D., Tewari, S. & Ranade, S. D., 05-05-2026, In: Journal of Molecular Structure. 1359, 145555.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Citation (Scopus) -
Crossing Boundaries: A Review of the Diverse Functions of Heterocyclic Compounds in the Management of Cancer and Infectious Diseases
Wal, P., Wal, A., Jawaid, T., Ganguly, P., Patel, B., Nainwal, P., Lari, M. Q., Kumar, A. & Kumar, D., 2026, In: Current Drug Targets. 26, 12, p. 850-866 17 p.Research output: Contribution to journal › Review article › peer-review
3 Link opens in a new tab Citations (Scopus) -
Current Treatment Approaches Against Lung Cancer
Kadiri, S. K., Shaik, M., Goyal, M., Faller, E., Kumar, D. & Tiwari, P., 2026, Coresource 4. Apple Academic Press, p. 83-106 24 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Decoding the molecular mechanism via systems biology-based insights into neoschaftoside from Ailanthus altissima targeting lung cancer
Gudasi, S., Kumar, D., Tewari, S., Kavalapure, R. S. & Ranade, S. D., 12-2026, In: Scientific Reports. 16, 1, 3328.Research output: Contribution to journal › Article › peer-review
Open Access