Working as Professor and Head of the department of Radiation Biology and Toxicology

Involved with research work on the effect of toxic metals especially lead. Study has been conducted in animal models as well as human samples.
Study conducted in animal model to investigate the dose-dependent lead-induced systemic changes in metabolism. Ours is the first study reported in in vivo model. As a part of this study, analysis of the pathway enrichment revealed abundance and significantly modulated metabolites associated with oxidative stress pathways. A study has been carried out in animal model to assess the lead-induced alterations on the haematological parameters and to understand the ameliorative effect of essential minerals on these alterations. The results of the study revealed a significant decrease (p < 0.001) in levels of hemoglobin (Hb) and δ-aminolevulinic acid dehydratase (δ-ALAD) and a significant increase (p < 0.001) in urinary δ-aminolevulinic acid (δ-ALAU) in subjects without mineral supplementation compared to those fed on a mineral-enriched diet. A positive correlation was observed between blood lead levels (PbB) and δ-ALAU (r = 0.792) and a negative correlation with Hb (r = −0.926) and δ-ALAD (r = −0.836) in the subjects. The observed alterations were more prominent in the animals which are fed on poor nutrition without any mineral supplements that those fed on the good nutrition with mineral supplements. Mineral supplementation with ongoing lead exposure can help to reduce the absorption lead and its associated effects.

Research work involved in the field of Toxicology, especially looking into the adverse effects of toxic metals like Lead. Our department has the facility to estimate the metal contents in Biological and environmental samples.

Having more than 20 years of teaching and research experience in the field of Biochemistry, Molecular biology and Toxicology