Laser Spectroscopy; Fluorescence Spectroscopy; Photoacoustic Spectroscopy; Protein autofluorescence;  Biomedical Research; Biomedical Device Development, Protein Fingerprinting, Low level laser therapy for tissue regeneration

Protein Finger Printing

Professor & Head, Department of Biophysics, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal - 576104

Awards and Recognition

• 2018-2020,  appointed  visiting fellow, QUT, Brisbane, Australia. 

• Dr. Mahato was awarded several merit based research fellowships, best poster awards in national and international conferences, international travel grants,

1. A system and method for identification of proteins in unstained PAGE (1D and 2D) by laser induced autofluorescence. Krishna Kishore Mahato, Manjunath  Siddaramaiah, Kapaettu Satyamoorthy, Manjunath B. Joshi, Anirbit, Datta, Subhash  Chandra. Application no.: 201641023520, dated 8th July  2016   (UTN: PT1716001), DBT/India.
2. Method and apparatus for optical microscopy using a mobile device. Nirmal Mazumder, Kapaettu Satyamoorthy, Mahato Krishna Kishore, Banik S, Vasudevan T G. Application no.: 201941031164, dated 1st August, 2019. DBT/India.
3. A method of Fabricating Microfluidic Device Sailendra K. Tiwary, Somashekara Bhat and Mahato Krishna Kishore. Application no.: 202141006368, dated 15th February, 2021. DBT/India.  
4. Method and imaging system for analysis of tissue specimen. Nirmal Mazumder, Spandana K U, Krishna Kishore Mahato, Sharada Rai, Kapaettu Satyamoorthy, Vasudevan T G. Application no.: 202141026979, dated 17th June, 2021. DBT/India.
5. Apparatus and method for identification of conformational and chemical change in non-enzymatically glycated proteins. Krishna Kishore Mahato, Darshan Chikkanayakanahalli Mukunda, Kapaettu Satyamoorthy, Nirmal Mazumder, Subhash Chandra. Application no.: 202141038896, dated 27th August, 2021. DBT/India.
6. A spectroscopic method for assessing the mitochondrial dysfunction. Krishna Kishore Mahato, Chandavalli Ramappa Raghushaker, K Satyamoorthy, Jackson Rodrigues, Satadru Ray. Application no.: 202111036808, dated 13th August, 2021. ICMR/India.
7. Photoacoustic spectroscopy and machine learning-based method to detect human breast tumor in xenografts. Krishna Kishore Mahato, Jackson Rodrigues, Stanley Mathew, Subhas Chandra. Application no.: 202211023646, dated 21st April 2022. ICMR/India.
8. A method for identification and classification of proteins based on autofluorescence. Krishna Kishore Mahato Darshan Chikkanayakanahalli Mukunda, Jackson Rodrigues, Subhash Chandra, Weena Stanley. Application no.: 202211031669, dated 2nd June, 2022. ICMR/India.
9. Optical device and method for breast lump preoperative diagnosis and intraoperative breast tumor margin assessment. Krishna Kishore Mahato, Stanley Mathew, Jackson Rodrigues, Subhash Chandra. Application no.: 20224103585, dated 22nd June, 2022. DBT/India.
10. Device and method for percutaneous breast lump diagnosis and intraoperative tumor positivity detection. Krishna Kishore Mahato, Stanley Mathew, Jackson Rodrigues, Subhash Chandra. Application no.: 202341000653, dated 4 January, 2023. DBT/ India.
11. System for tumour detection Krishna Kishore Mahato, Stanley Mathew, Jackson Rodrigues, Subhash Chandra. Application no.:202341017514, dated 15th March, 2023. DBT/India.
12. Photoacoustic probe for detecting cancer or other pathological disorder in breast. Krishna Kishore Mahato, Jackson Rodrigues, Satadru Ray, Subhash Chandra. Application no.:202341018911, Dated 20th March, 2023. DBT/ India.
13. A Thermoplastic starch (TPS) film and a method for preparing the same N. Mazumder, Pooja, Mahato K. K. Application no.:202341060541, dated 8th September, 2023. DBT/India.
14. A Method for preparation of starch-based bioplastic film with activated carbon. N. Mazumder, Pooja, Nafisa Yeshmin Ahmed, Neha P Santhosh, Sib Sankar Mal, Ishita Chakraborty, Mahato K. K. Application no.: 202341056528, dated 23rd August, 2023. DBT/India. 
15. Aseptic Transport Chamber/ Cage for Laboratory Applications. Krishna Kishore Mahato,  Jackson Rodrigues, Satadru Ray, Subhash Chandra. Application no.:202341018911, Dated 20th March, 2023. DBT/ India.
16. Systems and methods for breast cancer prediction based on fluorescence spectroscopy Krishna Kishore Mahato, Ashwini Amin, Jackson Rodrigues, Stanley Mathew, Satadru Ray, Subhash Chandra. Application no.: 202341082808, dated 5th December, 2023. DBT/ India.

• Commercialization of a photoacosutic probe under discussion with Murata Manufacturing Co., Ltd, through C-CAMP
• Industrial collaboration with Philips® in the development of fluorescence based oral cancer detection probe.
• Appointed as visiting faculty:  School of Electrical Engineering and Robotics, 2018-2020:  Queensland University of Technology (QUT), Brisbane, QLD 400, Brisbane, Australia.
• Invited talk (30th July – 4th August 2006)-Sixteenth Symposium on Thermo physical properties, held at the University of Colorado, Boulder, Colorado 80305-3328, USA- Funding by MAHE, Manipal, India.
• Attended and delivered talk at SPIE-BiOS Symposium held at San Francisco, California, USA (2-7th February, 2013) -  Awarded International Travel Grant for Senior Scientists category by Department of Science and Technology, Government of India. 
• Attended and delivered talk at SPIE-BIOS Symposium held at San Francisco, California, USA (1-6 February 2014)- Awarded with International Travel Grant, ICMR, Government of India. 
• Attended & delivered talk in an International Scientific Conference, Recent Trends and Future Perspectives Towards the Protection of Health, First World Hotel, Genting Highlands, Malaysia, 6-8th November, 2009.
• Attended and delivered an invited talk in Eighteenth Symposium on Thermophysical Properties, NIST, Boulder, Colorado, Colorado 80305-3337, USA. June 24-29, 2012.
• Visited- UKERI Faculty Exchange Programme for initiating Research Collaborations between Manipal Academy of Higher Education and University of Nottingham, Nottingham, United Kingdom during November 11-18, 2013.
• Consultant visit- to build laser induced fluorescence based instrumentation for cancer diagnosis. Department of Physics, King Abdualaziz University, Jeddah Saudi Arabia during 13-21, February 2015. 
• Consultant 2nd visit to build laser induced fluorescence based instrumentation for cancer diagnosis Department of Physics, King Abdualaziz University, Jeddah Saudi Arabia during 7-17, February 2016.
• Visited Collaborators meeting held at School of Electrical Engineering and Computer Science, Queensland University of Technology, Gardens Point, S Block, S1130- 42, 2 George Street, Brisbane, Australia, during 7-9 Feb 2018.
• Bilateral visit under Indo-Thai project (Fabrication of a Biodegradable Elastomeric Microfluidic Device (DST/INT/Thai/P-10/2019), King Mongut’s University of Technology, North Bangkok, Thailand, during 25-30 April, 2022. 
• Bilateral visit under Indo-Taiwan project (Multimodal nonlinear optical microscopy in studying articular cartilage regeneration and osteoarthritis, GITA/DST/TWN/P-95/2021), China Medical University, Taichung 404333, Taiwan, during 4-8 December, 2023.
• Best poster award at the fifth AACR International Conference on Frontiers in Cancer Prevention Research, Nov 12-15, 2006. Boston, MA, USA. Entitled “Photoacoustic spectroscopic aid in diagnosis of malignancy in ovarian tumors” by Rani A. Bhat; Sudha D. Kamath; Krishna K. Mahato*; Satadru Ray; V B. Kartha.
• Best poster award for the poster entitled, “Light Emitting Diode Induced Autofluorescence (LED-IAF) based interrogation of protein structures” by Darshan CM, Joshi VK, Subhash C, Nirmal M, Satyamoorthy K amd Mahato KK*, at the 87th Annual conference of Society of Biological Chemists (India), November 25-27, 2018.

• Professor &  Head from 2015 till date, at Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal Academy of Higher Education, Manipal – 576104.

• Professor &  Head from 2012 to till date, at Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal Academy of Higher Education, Manipal – 576104

• Associate Professor from 2007 - 2012, at Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal Academy of Higher Education, Manipal – 576104

• Associate Professor from 2007 - 2012, at School of Life Sciences, Manipal Academy of Higher Education, Manipal Academy of Higher Education, Manipal – 576104

• Assistant Professor from 2002 - 2007, at Kasturba Medical College, Manipal Academy of Higher Education, Manipal Academy of Higher Education, Manipal – 576104

• Project Scientist from 1999-2002, at Indian Institute of Technology, Kanpur