Research output per year
Research output per year
Personal profile
Experience
- Differentiation of neural stem cells and astrocytes from hiPSCs
- Development and optimization of standard protocols for the isolation, purification, and in vitro fluorescent tagging of extracellular vesicles from a variety of stem cells and from the serum
- Optimization of methods for the characterization of extracellular vesicles through a variety of molecular biology and analytical techniques
- Therapeutic application of extracellular vesicles in several neurodegenerative and neurological disease model
- Development of in vitro and in vivo based anti-inflammatory experiments and validation by ELISA
Professional Information
MEMBERSHIPS IN PROFESSIONAL SOCIETIES AND COMMITTEES, PUBLICATIONS
Member
- Society for Neurosci. (SFN), 2017-present.
- The American Society for Neural Therapy and Repair (ASNTR), 2018-present.
- International Society of Extracellular Vesicles (ISEV), 2019-present.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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An overview of the current advances in the treatment of inflammatory diseases using mesenchymal stromal cell secretome
Joshi, J. M., Muttigi, M. S., Upadhya, R. & Seetharam, R. N., 2023, In: Immunopharmacology and Immunotoxicology. 45, 4, p. 497-507 11 p.Research output: Contribution to journal › Review article › peer-review
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Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice
Attaluri, S., Jaimes Gonzalez, J., Kirmani, M., Vogel, A. D., Upadhya, R., Kodali, M., Madhu, L. N., Rao, S., Shuai, B., Babu, R. S., Huard, C. & Shetty, A. K., 2023, In: Frontiers in Aging Neuroscience. 15, 1200445.Research output: Contribution to journal › Article › peer-review
Open Access -
Brain-Specific Increase in Leukotriene Signaling Accompanies Chronic Neuroinflammation and Cognitive Impairment in a Model of Gulf War Illness
Attaluri, S., Upadhya, R., Kodali, M., Madhu, L. N., Upadhya, D., Shuai, B. & Shetty, A. K., 2022, In: Frontiers in Immunology. 13, p. 853000 1 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Proficiency of Extracellular Vesicles From hiPSC-Derived Neural Stem Cells in Modulating Proinflammatory Human Microglia: Role of Pentraxin-3 and miRNA-21-5p
Upadhya, R., 17-05-2022, In: Frontiers in Molecular Neuroscience. 15, p. 845542 845542.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Chronic VEGFR-3 signaling preserves dendritic arborization and sensitization under stress
Chakraborty, A., Upadhya, R., Usman, T. A., Shetty, A. K. & Rutkowski, J. M., 11-2021, In: Brain, Behavior, and Immunity. 98, p. 219-233 15 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)