Research output per year
Research output per year
- 28 results
Search results
-
2024
An in silico drug repurposing approach to identify HDAC1 inhibitors against glioblastoma
Gopinathan, A., Sankhe, R., Rathi, E., Kodi, T., Upadhya, R., Pai, K. S. R. & Kishore, A., 2024, (Accepted/In press) In: Journal of Biomolecular Structure and Dynamics.Research output: Contribution to journal › Article › peer-review
Open Access -
Cell-specific extracellular vesicle-encapsulated exogenous GABA controls seizures in epilepsy
R, A. B., K, S. R., Chandran, D., Hegde, S., Upadhya, R., SE, P. K., Shenoy, S., Devi, V. & Upadhya, D., 12-2024, In: Stem Cell Research and Therapy. 15, 1, 108.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
Influence of Ascorbic Acid on Di-(2-Ethylhexyl) Phthalate-induced Ovarian Gene Alterations in Pubertal Female Wistar Rats
Ali, S., Ziyad, A., Pai, K. S. R., Muraleedharan, A., Gopan, A., Upadhya, R., Seetharam, R. N. & Manokaran, K., 06-2024, In: Journal of Pharmacology and Pharmacotherapeutics. 15, 2, p. 190-199 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
An overview of the current advances in the treatment of inflammatory diseases using mesenchymal stromal cell secretome
Joshi, J. M., Muttigi, M. S., Upadhya, R. & Seetharam, R. N., 2023, In: Immunopharmacology and Immunotoxicology. 45, 4, p. 497-507 11 p.Research output: Contribution to journal › Review article › peer-review
1 Citation (Scopus) -
Global comparative transcriptomes uncover novel and population-specific gene expression in esophageal squamous cell carcinoma
Alotaibi, A., Gadekar, V. P., Gundla, P. S., Mandarthi, S., Jayendra, N., Tungekar, A., Lavanya, B. V., Bhagavath, A. K., Cordero, M. A. W., Pitkaniemi, J., Niazi, S. K., Upadhya, R., Bepari, A. & Hebbar, P., 12-2023, In: Infectious Agents and Cancer. 18, 1, 47.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice
Attaluri, S., Jaimes Gonzalez, J., Kirmani, M., Vogel, A. D., Upadhya, R., Kodali, M., Madhu, L. N., Rao, S., Shuai, B., Babu, R. S., Huard, C. & Shetty, A. K., 2023, In: Frontiers in Aging Neuroscience. 15, 1200445.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus) -
2022
Brain-Specific Increase in Leukotriene Signaling Accompanies Chronic Neuroinflammation and Cognitive Impairment in a Model of Gulf War Illness
Attaluri, S., Upadhya, R., Kodali, M., Madhu, L. N., Upadhya, D., Shuai, B. & Shetty, A. K., 2022, In: Frontiers in Immunology. 13, p. 853000 1 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Proficiency of Extracellular Vesicles From hiPSC-Derived Neural Stem Cells in Modulating Proinflammatory Human Microglia: Role of Pentraxin-3 and miRNA-21-5p
Upadhya, R., 17-05-2022, In: Frontiers in Molecular Neuroscience. 15, p. 845542 845542.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
2021
Chronic VEGFR-3 signaling preserves dendritic arborization and sensitization under stress
Chakraborty, A., Upadhya, R., Usman, T. A., Shetty, A. K. & Rutkowski, J. M., 11-2021, In: Brain, Behavior, and Immunity. 98, p. 219-233 15 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Extracellular vesicles for the diagnosis and treatment of Parkinson’s disease
Upadhya, R. & Shetty, A. K., 01-09-2021, In: Aging and Disease. 12, 6, p. 1438-1450 13 p.Research output: Contribution to journal › Review article › peer-review
Open Access48 Citations (Scopus) -
Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus
Kodali, M., Attaluri, S., Madhu, L. N., Shuai, B., Upadhya, R., Gonzalez, J. J., Rao, X. & Shetty, A. K., 02-2021, In: Aging Cell. 20, 2, e13277.Research output: Contribution to journal › Article › peer-review
Open Access77 Citations (Scopus) -
Oral Nano-Curcumin in a Model of Chronic Gulf War Illness Alleviates Brain Dysfunction with Modulation of Oxidative Stress, Mitochondrial Function, Neuroinflammation, Neurogenesis, and Gene Expression
Attaluri, S., Arora, M., Madhu, L. N., Kodali, M., Shuai, B., Melissari, L., Upadhya, R., Rao, X., Bates, A., Mitra, E., Ghahfarouk, K. R., Ravikumar, M. N. V. & Shetty, A. K., 03-10-2021, In: Aging and Disease. p. 1-31 31 p.Research output: Contribution to journal › Article › peer-review
-
2020
Astrocyte-derived extracellular vesicles: Neuroreparative properties and role in the pathogenesis of neurodegenerative disorders
Upadhya, R., Zingg, W., Shetty, S. & Shetty, A. K., 10-07-2020, In: Journal of Controlled Release. 323, p. 225-239 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access153 Citations (Scopus) -
Characterization, composition, and biological properties of extracellular vesicles generated from human induced pluripotent stem cell-derived neural stem cells
Upadhya, R., Madhu, L. N., Attaluri, S., Gitai, D., Pinson, M. R., Kodali, M., Shetty, G. A., Zanirati, G., Kumar, S., Shuai, B., Weintraub, S. T. & Shetty, A. K., 2020, Characterization, composition, and biological properties of extracellular vesicles generated from human induced pluripotent stem cell-derived neural stem cells. Philadalphia, USA.: International Society for Extracellular Vesicles, (ANNUAL MEETING ISEV 2020).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Open Access -
Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties
Upadhya, R., Madhu, L. N., Attaluri, S., Gitaí, D. L. G., Pinson, M. R., Kodali, M., Shetty, G., Zanirati, G., Kumar, S., Shuai, B., Weintraub, S. T. & Shetty, A. K., 01-01-2020, In: Journal of Extracellular Vesicles. 9, 1, 1809064.Research output: Contribution to journal › Article › peer-review
Open Access98 Citations (Scopus) -
Extracellular Vesicles in the Forebrain Display Reduced miR-346 and miR-331-3p in a Rat Model of Chronic Temporal Lobe Epilepsy
Gitaí, D. L. G., dos Santos, Y. D. R., Upadhya, R., Kodali, M., Madhu, L. N. & Shetty, A. K., 01-03-2020, In: Molecular Neurobiology. 57, 3, p. 1674-1687 14 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Intranasally administered human msc-derived extracellular vesicles pervasively incorporate into neurons and microglia in both intact and status epilepticus injured forebrain
Kodali, M., Castro, O. W., Kim, D. K., Thomas, A., Shuai, B., Attaluri, S., Upadhya, R., Gitai, D., Madhu, L. N., Prockop, D. J. & Shetty, A. K., 01-01-2020, In: International Journal of Molecular Sciences. 21, 1, 181.Research output: Contribution to journal › Article › peer-review
Open Access77 Citations (Scopus) -
Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro- and systemic inflammation in a model of Gulf War Illness
Shetty, A. K., Attaluri, S., Kodali, M., Shuai, B., Shetty, G. A., Upadhya, D., Hattiangady, B., Madhu, L. N., Upadhya, R., Bates, A. & Rao, X., 01-2020, In: Redox Biology. 28, 101389.Research output: Contribution to journal › Article › peer-review
Open Access39 Citations (Scopus) -
2019
A model of chronic temporal lobe epilepsy presenting constantly rhythmic and robust spontaneous seizures, co-morbidities and hippocampal neuropathology
Upadhya, D., Kodali, M., Gitai, D., Castro, O. W., Zanirati, G., Upadhya, R., Attaluri, S., Mitra, E., Shuai, B., Hattiangady, B. & Shetty, A. K., 01-01-2019, In: Aging and Disease. 10, 5, p. 915-936 22 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Citations (Scopus) -
Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood
Madhu, L. N., Attaluri, S., Kodali, M., Shuai, B., Upadhya, R., Gitai, D. & Shetty, A. K., 10-2019, In: Brain, Behavior, and Immunity. 81, p. 430-443 14 p.Research output: Contribution to journal › Article › peer-review
Open Access64 Citations (Scopus) -
Novel insights on systemic and brain aging, stroke, amyotrophic lateral sclerosis, and Alzheimer’s disease
Shetty, A. K., Upadhya, R., Madhu, L. N. & Kodali, M., 01-04-2019, In: Aging and Disease. 10, 2, p. 470-482 13 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Citations (Scopus) -
2018
Emerging anti-aging strategies – Scientific basis and efficacy
Shetty, A. K., Kodali, M., Upadhya, R. & Madhu, L. N., 2018, In: Aging and Disease. 9, 6, p. 1165-1184 20 p.Research output: Contribution to journal › Review article › peer-review
Open Access87 Citations (Scopus) -
Neural stem cell derived extracellular vesicles: Attributes and prospects for treating neurodegenerative disorders
Vogel, A., Upadhya, R. & Shetty, A. K., 12-2018, In: EBioMedicine. 38, p. 273-282 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access127 Citations (Scopus) -
Prospects of Cannabidiol for Easing Status Epilepticus-Induced Epileptogenesis and Related Comorbidities
Upadhya, D., Castro, O. W., Upadhya, R. & Shetty, A. K., 01-08-2018, In: Molecular Neurobiology. 55, 8, p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
2017
Distribution of mesenchymal stem cell-derived exosomes in the intact and injured brain following intranasal administration
Castro, O. W., Kodali, M., Upadhya, R., Kim, D. K., Shuai, B., Prockop, D. J. & Shetty, A. K., 15-11-2017, Distribution of mesenchymal stem cell-derived exosomes in the intact and injured brain following intranasal administration. Society for NeuroscienceResearch output: Chapter in Book/Report/Conference proceeding › Conference contribution
-
Early Curcumin Treatment After Exposure to Blast Shock Waves Prevents Long-term Cognitive and Memory Impairments and Maintains Higher Levels of Hippocampal Neurogenesis.
Upadhya, R., D, U., Hattiangady, B., ROBBINS, A., Kodali, M., Shuai, B., Bates, A., MORENO, M. & Shetty, A. K., 15-11-2017, Early curcumin treatment after exposure to blast shock waves prevents long-term cognitive and memory impairments and maintains higher levels of hippocampal neurogenesis. Society for NeuroscienceResearch output: Chapter in Book/Report/Conference proceeding › Conference contribution
-
2011
Evaluation of pharmacokinetic, biodistribution, pharmacodynamic, and toxicity profile of free juglone and its sterically stabilized liposomes
Aithal, B. K., Sunil Kumar, M. R., Rao, B. N., Upadhya, R., Prabhu, V., Shavi, G., Arumugam, K., Sajankila, S. P., Udupa, N., Satyamoorthy, K. & Satish Rao, B. S., 2011, In: Journal of Pharmaceutical Sciences. 100, 8, p. 3517-3528 12 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus) -
γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines
Kumar, A., Rai, P. S., Upadhya, R., Vishwanatha, Shama Prasada, K., Satish Rao, B. S. & Satyamoorthy, K., 11-2011, In: International Journal of Radiation Biology. 87, 11, p. 1086-1096 11 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus)