Personal profile
Professional Information
- Served as Consultant (Technical expert) for Stempeutics Research Pvt Ltd
- Member of IEC committee: Serving as Stem cell expert in the Intitutional ethics committee, MAHE
- Member of IBSC committee: Serving as committee member, IBSC, Stempeutics Research Pvt Ltd
Research interests
· Understanding epigenetic deregulation in oral and cervical cancer
· Developing methylation-based biomarkers for screening and early diagnosis of oral and cervical cancer
· Understanding and elucidating the signalling pathways, crosstalk’s between key regulatory molecules and their molecular mechanisms in cancer
· Large scale manufacturing of adult stem cells for clinical applications, process development studies, understanding the mechanism of action of mesenchymal stem cells and its applications in treatment of various disease indications, formulation development studies for biotherapeutic product development
· Development and Evaluation of a Mesenchymal Stromal Cell Secretome Based Nano formulation for the Treatment of Skin diseases
Experience
- August 2024 onwards: Assistant Professor, Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Manipal
- April 2023- August 2024 : Deputy Manager and In charge of Production Department at Stempeutics Research Pvt. Ltd.
- April 2020- April 2023: Senior Research Scientist at Stempeutics Research Pvt. Ltd.
- December 2015- April 2020: Research Scientist at Stempeutics Research Pvt. Ltd.
- November 2010 to August 2015: Senior Research Fellow (CSIR) and PhD Scholar, School of Life Sciences, Manipal University
Awards and recognition:
1. Dr. Vidya Ravi Memorial award for top Women Scientist in Stem Cell Therapy presented by Maruti Hospital, Department of Stem Cell Therapy and Regenerative Medicine, Trichy, Tamilnadu in the year 2024
2. Serving as a member of Institutional Ethics Committee of Kasturba Medical College and Kasturba Hospital as an “Expert in stem cell research” from September 2024.
3. Dr. T M A Pai Gold Medal award for outstanding research publication for the year 2023 in appreciation for excellence in research presented by Manipal School of Life Sciences, MAHE, Manipal
4. Dr. T M A Pai Gold Medal award for outstanding research publication for the year 2021 in appreciation for excellence in research presented by Manipal School of Life Sciences, MAHE, Manipal
5. Certificate of appreciation for outstanding research publication for the year 2022 presented by Manipal School of Life Sciences, MAHE, Manipal
6. “Certificate of Recognition” award presented by Stempeutics Research Pvt Ltd in March 2022 for outstanding contribution to the organization.
7. “Employee of the Month” award presented by Stempeutics Research Pvt Ltd in August 2018 for excellence, dedication and outstanding performance
8. Recipient of CSIR-SRF Fellowship
9. “Young investigator award” at the 10th Asia Pacific Conference on Human Genetics held in Kuala Lumpur, Malaysia, December 5th-8th ,2012, for the paper entitled “Double C2 like domain beta (DOC2B) is down regulated through promoter hyper methylation and acts as a tumor suppressor in cervical carcinoma
10. “Best poster award” at Manipal University Scientific meet held on 12th January 2013
11. “Best poster award” at 10th Indo-Australian workshop on Epithelial Development, Function and Disease New Frontiers and Therapies held at Manipal University, Manipal from April 11th to13st 2014.
12. Invention award, awarded by Intellectual Ventures India, Bangalore for the inventions entitled
- “Increased DNA methylation of specific genes & decreased expression of corresponding proteins as novel non-invasive diagnostic biomarkers for cervical cancer” (Invention ID: IN-800856)
- “Specific genes with altered DNA methylation as biomarkers for diagnosis of oral cancer. Methylation regulated genes as diagnostic and prognostic marker for early detection of oral cancer” (Invention ID: IN-800857)
- “Specific genes with increased DNA methylation as biomarkers for diagnosis of cervical cancer” (Invention ID: IN-800855)
13. Travel Grant to attend 10th Asia Pacific Conference on Human Genetics held in Kuala Lumpur, Malaysia, December 5th-8th, 2012
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Circular RNAs in colorectal cancer: Emerging insights and future perspectives
Behera, R., Khandelwal, A., Devi, V., Mascarenhas, R., Bhat, S., Mukhopadhyay, A. & Kabekkodu, S. P., 01-2026, In: Biochemical Pharmacology. 243, 117495.Research output: Contribution to journal › Review article › peer-review
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Mesenchymal stromal cells and their derivatives: A regenerative frontier in burn wound healing
Verma, S., Upadhya, R., Bhat, S. & Neelavar Seetharam, R., 04-06-2026, In: Biochemical and Biophysical Research Communications. 816, 153653.Research output: Contribution to journal › Review article › peer-review
Open Access -
Mesenchymal stromal cell secretome in skin health: A comprehensive review of composition, mechanisms, and dermatological applications
Bucha, K., Molugulu, Y., Talawar, S. P., Shetty, N. V. & Bhat, S., 06-2026, In: Materials Today Advances. 30, 100816.Research output: Contribution to journal › Review article › peer-review
Open Access -
Biological functions of extracellular vesicle double C2-like domain beta in cervical cancer
Eswaran, S., Bhat, S., Upadhya, D., Mascarenhas, R. & Kabekkodu, S. P., 12-2025, In: Scientific Reports. 15, 1, 477.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
Inflammatory priming of mesenchymal stromal cells enhances its secretome potential through secretion of anti-inflammatory and ECM modulating factors: Insights into proteomic and functional properties
Joshi, J. M., Verma, S., Upadhya, R., Bhat, S. & Seetharam, R. N., 08-09-2025, In: Biochemical and Biophysical Research Communications. 778, 152391.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Citations (Scopus)