1,8-naphthyridine derivatives: A privileged scaffold for versatile biological activities

Madhwi Ojha, Divya Yadav, Avinash Kumar, Suman Dasgupta, Rakesh Yadav

Research output: Contribution to journalReview articlepeer-review

11 Citations (Scopus)


1, 8-Naphthyridine nucleus belongs to significant nitrogen-containing heterocyclic compounds which has garnered the interest of researchers due to its versatile biological activities. It is known to be used as an antimicrobial, anti-psychotic, anti-depressant, anti-convulsant, anti-Alzheimer’s, anti-cancer, analgesic, anti-inflammatory, antioxidant, anti-viral, anti-hypertensive, anti-malarial, pesticides, anti-platelets, and CB2 receptor agonist, etc. The present review highlights the framework of biological properties of synthesized 1, 8-naphthyridine derivatives developed by various research groups across the globe.

Original languageEnglish
Pages (from-to)576-591
Number of pages16
JournalMini-Reviews in Medicinal Chemistry
Issue number5
Publication statusPublished - 2021
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • Cancer Research


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