3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione

Hemmige S. Yathirajan; Kuriya M. Lokanatha Rai; Santhosh L. Gaonkar; Rajenahally S. Narasegowda; Basappa Prabhuswamy; Michael Bolte

doi:10.1107/S1600536804033951

3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione

Hemmige S. Yathirajan
, Kuriya M. Lokanatha Rai
, Santhosh L. Gaonkar
, Rajenahally S. Narasegowda
, Basappa Prabhuswamy
, Michael Bolte^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The structural properties of C₁₀H₈N₂O ₄S compound were studied. The compound was investigated as a PPAR-γ-agonist that leads to the development of several insulin-sensitizing drugs for the treatment of diabetes. The compound serves as a starting material for the synthesis of antihyperglycemic pharmaceuticals. It was observed that the planar thiazolidine-2,4-dione ring is almost perpendicular to the nitrophenyl ring in the compound, which describes its crystal structure.

Original language	English
Pages (from-to)	o245-o246
Journal	Acta Crystallographica Section E: Structure Reports Online
Volume	61
Issue number	2
DOIs	https://doi.org/10.1107/S1600536804033951
Publication status	Published - 02-2005

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

General Chemistry
General Materials Science
Condensed Matter Physics

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10.1107/S1600536804033951

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title = "3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione",

abstract = "The structural properties of C10H8N2O 4S compound were studied. The compound was investigated as a PPAR-γ-agonist that leads to the development of several insulin-sensitizing drugs for the treatment of diabetes. The compound serves as a starting material for the synthesis of antihyperglycemic pharmaceuticals. It was observed that the planar thiazolidine-2,4-dione ring is almost perpendicular to the nitrophenyl ring in the compound, which describes its crystal structure.",

author = "Yathirajan, \{Hemmige S.\} and \{Lokanatha Rai\}, \{Kuriya M.\} and Gaonkar, \{Santhosh L.\} and Narasegowda, \{Rajenahally S.\} and Basappa Prabhuswamy and Michael Bolte",

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month = feb,

doi = "10.1107/S1600536804033951",

language = "English",

volume = "61",

pages = "o245--o246",

journal = "Acta Crystallographica Section E: Structure Reports Online",

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publisher = "International Union of Crystallography",

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TY - JOUR

T1 - 3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione

AU - Yathirajan, Hemmige S.

AU - Lokanatha Rai, Kuriya M.

AU - Gaonkar, Santhosh L.

AU - Narasegowda, Rajenahally S.

AU - Prabhuswamy, Basappa

AU - Bolte, Michael

PY - 2005/2

Y1 - 2005/2

N2 - The structural properties of C10H8N2O 4S compound were studied. The compound was investigated as a PPAR-γ-agonist that leads to the development of several insulin-sensitizing drugs for the treatment of diabetes. The compound serves as a starting material for the synthesis of antihyperglycemic pharmaceuticals. It was observed that the planar thiazolidine-2,4-dione ring is almost perpendicular to the nitrophenyl ring in the compound, which describes its crystal structure.

AB - The structural properties of C10H8N2O 4S compound were studied. The compound was investigated as a PPAR-γ-agonist that leads to the development of several insulin-sensitizing drugs for the treatment of diabetes. The compound serves as a starting material for the synthesis of antihyperglycemic pharmaceuticals. It was observed that the planar thiazolidine-2,4-dione ring is almost perpendicular to the nitrophenyl ring in the compound, which describes its crystal structure.

UR - https://www.scopus.com/pages/publications/18544374869

UR - https://www.scopus.com/pages/publications/18544374869#tab=citedBy

U2 - 10.1107/S1600536804033951

DO - 10.1107/S1600536804033951

M3 - Article

AN - SCOPUS:18544374869

SN - 1600-5368

VL - 61

SP - o245-o246

JO - Acta Crystallographica Section E: Structure Reports Online

JF - Acta Crystallographica Section E: Structure Reports Online

IS - 2

ER -

3-(p-Nitrobenzyl)-1,3-thiazolidine-2,4-dione

Abstract

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