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3D printing in personalized medicines: A focus on applications of the technology

  • Pavan Kalyan BG
  • , Sonal Mehrotra
  • , Shirleen Miriam Marques
  • , Lalit Kumar*
  • , Ruchi Verma
  • *Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Personalized medicines connect a new frontier for developing customizable therapeutic formulations that consider an individual's genetic composition, medical history, and physiology. Precision medicines have acquired a foothold in the pharmaceutical sector thanks for incorporating revolutionary 3D printing technology. Compared to conventional methods, 3D printing permits rapid manufacturing, design, and bioprinting. Pharmaceutical manufacturers are enticed to construct compositions via layer-by-layer deposition of a predefined adaptable polymer in various geometries, thicknesses, release profiles, and customizable designs. As this unified, innovative technology progresses, the optimized patient-centric medical devices, prostheses, and implants must adhere to regulatory norms and requirements to proceed to the marketplace. This review explores the fundamentals of 3D printing before expanding on to the methods and strategies. The central beam of light is put on the rationale for personalized medicines. Applications of 3D printing integrated customized delivery and devices include dose personalization, multidrug composition, modified release system, medical implants, and particular demographic-specific customization. Finally, a few hurdles and regulatory perspectives of 3D printing in developing tailored medications are discussed.

Original languageEnglish
Article number105875
JournalMaterials Today Communications
Volume35
DOIs
Publication statusPublished - 06-2023

All Science Journal Classification (ASJC) codes

  • General Materials Science
  • Mechanics of Materials
  • Materials Chemistry

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