3D QSAR studies of N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones: A novel class of antibacterial agents

B. B. Lohray; Neha Gandhi; Brijesh Kumar Srivastava; Vidya Bhushan Lohray

doi:10.1016/j.bmcl.2006.04.023

3D QSAR studies of N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones: A novel class of antibacterial agents

B. B. Lohray^*
, Neha Gandhi
, Brijesh Kumar Srivastava
, Vidya Bhushan Lohray

^*Corresponding author for this work

School of Computer Engineering

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

Three-dimensional QSAR studies for N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones were conducted using TSAR 3.3. The in vitro activities (MICs) of the compounds against Staphylococcus aureus ATCC 25923 exhibited a strong correlation with the prediction made by the model developed in the present study.

Original language	English
Pages (from-to)	3817-3823
Number of pages	7
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	16
Issue number	14
DOIs	https://doi.org/10.1016/j.bmcl.2006.04.023
Publication status	Published - 15-07-2006

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/j.bmcl.2006.04.023

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title = "3D QSAR studies of N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones: A novel class of antibacterial agents",

abstract = "Three-dimensional QSAR studies for N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones were conducted using TSAR 3.3. The in vitro activities (MICs) of the compounds against Staphylococcus aureus ATCC 25923 exhibited a strong correlation with the prediction made by the model developed in the present study.",

author = "Lohray, \{B. B.\} and Neha Gandhi and Srivastava, \{Brijesh Kumar\} and Lohray, \{Vidya Bhushan\}",

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T2 - A novel class of antibacterial agents

AU - Lohray, B. B.

AU - Gandhi, Neha

AU - Srivastava, Brijesh Kumar

AU - Lohray, Vidya Bhushan

PY - 2006/7/15

Y1 - 2006/7/15

N2 - Three-dimensional QSAR studies for N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones were conducted using TSAR 3.3. The in vitro activities (MICs) of the compounds against Staphylococcus aureus ATCC 25923 exhibited a strong correlation with the prediction made by the model developed in the present study.

AB - Three-dimensional QSAR studies for N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones were conducted using TSAR 3.3. The in vitro activities (MICs) of the compounds against Staphylococcus aureus ATCC 25923 exhibited a strong correlation with the prediction made by the model developed in the present study.

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UR - https://www.scopus.com/pages/publications/33746758901#tab=citedBy

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DO - 10.1016/j.bmcl.2006.04.023

M3 - Article

C2 - 16650983

AN - SCOPUS:33746758901

SN - 0960-894X

VL - 16

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JO - Bioorganic and Medicinal Chemistry Letters

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IS - 14

ER -

3D QSAR studies of N-4-arylacryloylpiperazin-1-yl-phenyl-oxazolidinones: A novel class of antibacterial agents

Abstract

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