A comprehensive review on the functional role of miRNA clusters in cervical cancer

Srinath Sriharikrishnaa, Femi E. John, Medha Bairy, Sachin Shetty, Padmanaban S. Suresh, Shama P. Kabekkodu

Research output: Contribution to journalReview articlepeer-review

Abstract

Plain language summary: Cervical cancer is a major global health concern, mostly caused by human papillomavirus infection, resulting in a high number of new cases and fatalities annually. This review examines the role of specific genetic variables known as microRNA clusters (MCs) in the development and progression of cervical cancer. The MCs harbor many microRNAs that control genes related to tumor proliferation, infiltration and dissemination. Understanding the functioning of these MCs can aid in early diagnosis of cervical cancer and predicting its patterns of behavior. We explore the potential benefits of assessing MC expression levels in cancer staging and prognosis, and the development of diagnostic tools and treatments. Targeting these molecular targets could provide interesting opportunities for future cancer treatments.

Original languageEnglish
Pages (from-to)493-511
Number of pages19
JournalEpigenomics
Volume16
Issue number7
DOIs
Publication statusPublished - 01-04-2024

All Science Journal Classification (ASJC) codes

  • Genetics
  • Cancer Research

Fingerprint

Dive into the research topics of 'A comprehensive review on the functional role of miRNA clusters in cervical cancer'. Together they form a unique fingerprint.

Cite this