A Comprehensive Review on Thiophene Based Chemosensors

Rikitha S. Fernandes, Nitinkumar S. Shetty, Priyanka Mahesha, Santhosh L. Gaonkar

Research output: Contribution to journalReview articlepeer-review

9 Citations (Scopus)


The recognition and sensing of various analytes in aqueous and biological systems by using fluorometric or colorimetric chemosensors possessing high selectivity and sensitivity, low cost has gained enormous attention. Furthermore, thiophene derivatives possess exceptional photophysical properties compared to other heterocycles, and therefore they can be employed in chemosensors for analyte detection. In this review, we have tried to explore the design and detection mechanism of various thiophene-based probes, practical applicability, and their advanced models (design guides), which could be thoughtful for the synthesis of new thiophene-based probes. This review provides an insight into the reported chemosensors (2008-2020) for thiophene scaffold as effective emission and absorption-based chemosensors.

Original languageEnglish
Pages (from-to)19-56
Number of pages38
JournalJournal of Fluorescence
Issue number1
Publication statusPublished - 01-2022

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Spectroscopy
  • Clinical Biochemistry


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