This study aims at developing a clinically oriented automated diagnostic tool for distin-guishing malignant melanocytic lesions from benign melanocytic nevi in diverse image databases. Due to the presence of artifacts, smooth lesion boundaries, and subtlety in diagnostic features, the accuracy of such systems gets hampered. Thus, the proposed framework improves the accuracy of melanoma detection by combining the clinical aspects of dermoscopy. Two methods have been adopted for achieving the aforementioned objective. Firstly, artifact removal and lesion localization are performed. In the second step, various clinically significant features such as shape, color, tex-ture, and pigment network are detected. Features are further reduced by checking their individual significance (i.e., hypothesis testing). These reduced feature vectors are then classified using SVM classifier. Features specific to the domain have been used for this design as opposed to features of the abstract images. The domain knowledge of an expert gets enhanced by this methodology. The proposed approach is implemented on a multi-source dataset (PH2 + ISBI 2016 and 2017) of 515 annotated images, thereby resulting in sensitivity, specificity and accuracy of 83.8%, 88.3%, and 86%, respectively. The experimental results are promising, and can be applied to detect asymmetry, pigment network, colors, and texture of the lesions.

Original languageEnglish
Article number4243
JournalApplied Sciences (Switzerland)
Issue number9
Publication statusPublished - 01-05-2022

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Instrumentation
  • Engineering(all)
  • Process Chemistry and Technology
  • Computer Science Applications
  • Fluid Flow and Transfer Processes


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