A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives

S. L. Gaonkar; K. M. Lokanatha Rai

doi:10.1016/j.tetlet.2005.06.007

A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives

S. L. Gaonkar
, K. M. Lokanatha Rai^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.

Original language	English
Pages (from-to)	5969-5970
Number of pages	2
Journal	Tetrahedron Letters
Volume	46
Issue number	35
DOIs	https://doi.org/10.1016/j.tetlet.2005.06.007
Publication status	Published - 29-08-2005

All Science Journal Classification (ASJC) codes

Biochemistry
Organic Chemistry
Drug Discovery

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10.1016/j.tetlet.2005.06.007

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title = "A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives",

abstract = "The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.",

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Y1 - 2005/8/29

N2 - The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.

AB - The reaction of ketohydrazones containing an α-methylene group with chloramine-T followed by treatment with triethylamine leads to the formation of azoalkenes via an α-chloroazo-compound, which can react intermolecularly and in situ with olefinic compounds to produce tetrahydropyridazine derivatives in good yield.

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UR - https://www.scopus.com/pages/publications/23044478807#tab=citedBy

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DO - 10.1016/j.tetlet.2005.06.007

M3 - Article

AN - SCOPUS:23044478807

SN - 0040-4039

VL - 46

SP - 5969

EP - 5970

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 35

ER -

A new method for the generation of azoalkenes from ketohydrazones and its application to the synthesis of tetrahydropyridazine derivatives

Abstract

All Science Journal Classification (ASJC) codes

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