A NEW MICROWAVE-ASSISTED METHOD FOR THE SYNTHESIS OF 2-SUBSTITUTED-THIAZOL-4(5H)-ONE VIA HANTZSCH CONDENSATION

Swarnagowri Nayak, Santosh L. Gaonkar

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

A new microwave-assisted method is developed for the synthesis of 2-substituted-thiazol-4(5H)-ones via Hantzsch condensation by a simple experimental protocol without using any catalyst. The products were isolated in excellent yield without any purification. Synthesized compounds were characterized by applying FTIR,1 H NMR,13 C NMR, and mass spectral studies and a plausible mechanism is proposed for the formation of the product. The method is versatile for the preparation of a new class of 2-substituted-thiazol-4(5H)-ones.

Original languageEnglish
Pages (from-to)310-315
Number of pages6
JournalRasayan Journal of Chemistry
Volume15
Issue number1
DOIs
Publication statusPublished - 01-01-2022

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • Biochemistry
  • General Chemical Engineering
  • General Energy
  • Pharmacology, Toxicology and Pharmaceutics(all)

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