A novel route for the synthesis of impurities C and G of antihypertensive drug timolol maleate

Mugdha Suryawanshi; Gauri Babhulkar; Bharat Satpute; Tejal Patil; Santosh Chindhe; Deepak Pawar; Dileep Kumar; Rajesh Rane

doi:10.56042/ijc.v63i7.7519

A novel route for the synthesis of impurities C and G of antihypertensive drug timolol maleate

Mugdha Suryawanshi
, Gauri Babhulkar
, Bharat Satpute
, Tejal Patil
, Santosh Chindhe
, Deepak Pawar
, Dileep Kumar
, Rajesh Rane^*

^*Corresponding author for this work

Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

Abstract

In this short communication has been described the synthesis and characterization of C and G impurities of Timolol maleate. The recent study introduces the initial synthesis of these impurities with both high yield and high purity. The purity of the impurities have been validated through High-Performance Liquid Chromatography (HPLC), while their structures have been determined utilizing ^1H NMR and mass spectroscopy.

Original language	English
Pages (from-to)	732-736
Number of pages	5
Journal	Indian Journal of Chemistry (IJC)
Volume	63
Issue number	7
DOIs	https://doi.org/10.56042/ijc.v63i7.7519
Publication status	Published - 01-07-2024

All Science Journal Classification (ASJC) codes

General Pharmacology, Toxicology and Pharmaceutics
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.56042/ijc.v63i7.7519

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AU - Suryawanshi, Mugdha

AU - Babhulkar, Gauri

AU - Satpute, Bharat

AU - Patil, Tejal

AU - Chindhe, Santosh

AU - Pawar, Deepak

AU - Kumar, Dileep

AU - Rane, Rajesh

PY - 2024/7/1

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AB - In this short communication has been described the synthesis and characterization of C and G impurities of Timolol maleate. The recent study introduces the initial synthesis of these impurities with both high yield and high purity. The purity of the impurities have been validated through High-Performance Liquid Chromatography (HPLC), while their structures have been determined utilizing 1H NMR and mass spectroscopy.

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A novel route for the synthesis of impurities C and G of antihypertensive drug timolol maleate

Abstract

All Science Journal Classification (ASJC) codes

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