TY - JOUR
T1 - A Rare Case of Adult Embryonal Rhabdomyosarcoma of the Uterus in a Postmenopausal Woman
AU - Paturi, Bhaavya
AU - Doddapaneni, Praharshita
AU - Guruvare, Shyamala
AU - Usman, Nawaz
AU - Udupa, Karthik
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Indian Association of Surgical Oncology 2024.
PY - 2024
Y1 - 2024
N2 - Rhabdomyosarcoma is a malignant soft tissue tumor arising from undifferentiated myogenic progenitor cells, predominantly occurring in children. Here, we report a peculiar case of adult rhabdomyosarcoma of the uterus in a postmenopausal lady, who presented with heaviness in the lower abdomen and a large abdominopelvic mass. In this article, we discuss the difficulty in diagnosing such cases and the crucial role of immunohistochemistry. This case report highlights the importance of considering rhabdomyosarcoma as a differential diagnosis in atypical soft tissue tumors, especially in postmenopausal women. Rhabdomyosarcoma of the uterus in adults being very rare, there is limited data on the appropriate management guidelines. Our patient received multimodality treatment with surgery followed by palliative chemotherapy and radiotherapy for recurrence of the disease. As rhabdomyosarcoma is very aggressive, prognosis is often poor. Hence, early diagnosis and prompt initiation of multidisciplinary treatment offer the best chance of survival for these patients.
AB - Rhabdomyosarcoma is a malignant soft tissue tumor arising from undifferentiated myogenic progenitor cells, predominantly occurring in children. Here, we report a peculiar case of adult rhabdomyosarcoma of the uterus in a postmenopausal lady, who presented with heaviness in the lower abdomen and a large abdominopelvic mass. In this article, we discuss the difficulty in diagnosing such cases and the crucial role of immunohistochemistry. This case report highlights the importance of considering rhabdomyosarcoma as a differential diagnosis in atypical soft tissue tumors, especially in postmenopausal women. Rhabdomyosarcoma of the uterus in adults being very rare, there is limited data on the appropriate management guidelines. Our patient received multimodality treatment with surgery followed by palliative chemotherapy and radiotherapy for recurrence of the disease. As rhabdomyosarcoma is very aggressive, prognosis is often poor. Hence, early diagnosis and prompt initiation of multidisciplinary treatment offer the best chance of survival for these patients.
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U2 - 10.1007/s13193-024-02133-3
DO - 10.1007/s13193-024-02133-3
M3 - Article
AN - SCOPUS:85210493777
SN - 0975-7651
JO - Indian Journal of Surgical Oncology
JF - Indian Journal of Surgical Oncology
ER -