TY - JOUR
T1 - A review on allopathic and herbal nanofibrous drug delivery vehicles for cancer treatments
AU - Mateti, Tarun
AU - Aswath, Surabhi
AU - Vatti, Anoop Kishore
AU - Kamath, Agneya
AU - Laha, Anindita
N1 - Funding Information:
We would like to express our gratitude to the Manipal Institute of Technology and Manipal Academy of Higher Education in Manipal for allowing us to undertake this research.
Publisher Copyright:
© 2021
PY - 2021/9
Y1 - 2021/9
N2 - Drug delivery empowered with nanotechnology manifests to be a superior therapy to cancer. Electrospun nanofibers cocooning anti-cancerous drugs have shown tremendous cytotoxicity towards various tumor cells, including breast, brain, liver, and lung cancer cells. This pristine drug delivery system, according to literature, desists showing any undesirable effects on other parts of the body and bestows several other benefits. From nature-derived Curcumin to laboratory-made Doxorubicin, literature proclaims many such drugs used in nanofibrous drug delivery. Also, multi-drug delivery has been reported to exhibit enhanced properties. The present review exhibits the unrealized potential of nanofibrous drug delivery in chemotherapy.
AB - Drug delivery empowered with nanotechnology manifests to be a superior therapy to cancer. Electrospun nanofibers cocooning anti-cancerous drugs have shown tremendous cytotoxicity towards various tumor cells, including breast, brain, liver, and lung cancer cells. This pristine drug delivery system, according to literature, desists showing any undesirable effects on other parts of the body and bestows several other benefits. From nature-derived Curcumin to laboratory-made Doxorubicin, literature proclaims many such drugs used in nanofibrous drug delivery. Also, multi-drug delivery has been reported to exhibit enhanced properties. The present review exhibits the unrealized potential of nanofibrous drug delivery in chemotherapy.
UR - http://www.scopus.com/inward/record.url?scp=85114148629&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85114148629&partnerID=8YFLogxK
U2 - 10.1016/j.btre.2021.e00663
DO - 10.1016/j.btre.2021.e00663
M3 - Review article
AN - SCOPUS:85114148629
SN - 2215-017X
VL - 31
JO - Biotechnology Reports
JF - Biotechnology Reports
M1 - e00663
ER -
