A study on hemodialyzer membranes using finite element analysis

Ahana Fatima Alex; R. Vinoth; Ravishankar Dudhe

doi:10.1109/ASET48392.2020.9118354

A study on hemodialyzer membranes using finite element analysis

Ahana Fatima Alex
, R. Vinoth
, Ravishankar Dudhe

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Citations (Scopus)

Abstract

A high flux membrane is modelled for hemodialyzers. The function of high flux membrane is simulated to observe its role in overall toxin clearance and retaining necessary solutes. In this study, hemodialyzer with a single membrane and multiple membranes are modelled using Finite element method. Toxin clearance is observed by varying different geometric parameters of the hollow fiber and velocity profile of the fluids such as blood and dialysate. Parameters are varied using combinations as per Taguchi algorithm for obtaining optimal results. Dialyzer with multiple membranes showed 20.97% better urea clearance than single membrane. Therefore, this design was further considered for the study of six solutes having different molecular weight ranging from low to high. Results shows that a multi layered membrane have better variance in toxin clearance than single layered hollow fiber membrane though loss of Albumin remains the same.

Original language	English
Title of host publication	2020 Advances in Science and Engineering Technology International Conferences, ASET 2020
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781728146409
DOIs	https://doi.org/10.1109/ASET48392.2020.9118354
Publication status	Published - 02-2020
Event	2020 Advances in Science and Engineering Technology International Conferences, ASET 2020 - Dubai, United Arab Emirates Duration: 04-02-2020 → 09-04-2020

Publication series

Name	2020 Advances in Science and Engineering Technology International Conferences, ASET 2020

Conference

Conference	2020 Advances in Science and Engineering Technology International Conferences, ASET 2020
Country/Territory	United Arab Emirates
City	Dubai
Period	04-02-20 → 09-04-20

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 7 Affordable and Clean Energy

All Science Journal Classification (ASJC) codes

Electrical and Electronic Engineering
Industrial and Manufacturing Engineering
Mechanical Engineering
Waste Management and Disposal
Process Chemistry and Technology
Artificial Intelligence
Energy Engineering and Power Technology
Renewable Energy, Sustainability and the Environment

Access to Document

10.1109/ASET48392.2020.9118354

Cite this

Alex, A. F., Vinoth, R., & Dudhe, R. (2020). A study on hemodialyzer membranes using finite element analysis. In 2020 Advances in Science and Engineering Technology International Conferences, ASET 2020 Article 9118354 (2020 Advances in Science and Engineering Technology International Conferences, ASET 2020). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ASET48392.2020.9118354

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title = "A study on hemodialyzer membranes using finite element analysis",

abstract = "A high flux membrane is modelled for hemodialyzers. The function of high flux membrane is simulated to observe its role in overall toxin clearance and retaining necessary solutes. In this study, hemodialyzer with a single membrane and multiple membranes are modelled using Finite element method. Toxin clearance is observed by varying different geometric parameters of the hollow fiber and velocity profile of the fluids such as blood and dialysate. Parameters are varied using combinations as per Taguchi algorithm for obtaining optimal results. Dialyzer with multiple membranes showed 20.97\% better urea clearance than single membrane. Therefore, this design was further considered for the study of six solutes having different molecular weight ranging from low to high. Results shows that a multi layered membrane have better variance in toxin clearance than single layered hollow fiber membrane though loss of Albumin remains the same.",

author = "Alex, \{Ahana Fatima\} and R. Vinoth and Ravishankar Dudhe",

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doi = "10.1109/ASET48392.2020.9118354",

language = "English",

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Alex, AF, Vinoth, R & Dudhe, R 2020, A study on hemodialyzer membranes using finite element analysis. in 2020 Advances in Science and Engineering Technology International Conferences, ASET 2020., 9118354, 2020 Advances in Science and Engineering Technology International Conferences, ASET 2020, Institute of Electrical and Electronics Engineers Inc., 2020 Advances in Science and Engineering Technology International Conferences, ASET 2020, Dubai, United Arab Emirates, 04-02-20. https://doi.org/10.1109/ASET48392.2020.9118354

A study on hemodialyzer membranes using finite element analysis. / Alex, Ahana Fatima; Vinoth, R.; Dudhe, Ravishankar.
2020 Advances in Science and Engineering Technology International Conferences, ASET 2020. Institute of Electrical and Electronics Engineers Inc., 2020. 9118354 (2020 Advances in Science and Engineering Technology International Conferences, ASET 2020).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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T1 - A study on hemodialyzer membranes using finite element analysis

AU - Alex, Ahana Fatima

AU - Vinoth, R.

AU - Dudhe, Ravishankar

PY - 2020/2

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N2 - A high flux membrane is modelled for hemodialyzers. The function of high flux membrane is simulated to observe its role in overall toxin clearance and retaining necessary solutes. In this study, hemodialyzer with a single membrane and multiple membranes are modelled using Finite element method. Toxin clearance is observed by varying different geometric parameters of the hollow fiber and velocity profile of the fluids such as blood and dialysate. Parameters are varied using combinations as per Taguchi algorithm for obtaining optimal results. Dialyzer with multiple membranes showed 20.97% better urea clearance than single membrane. Therefore, this design was further considered for the study of six solutes having different molecular weight ranging from low to high. Results shows that a multi layered membrane have better variance in toxin clearance than single layered hollow fiber membrane though loss of Albumin remains the same.

AB - A high flux membrane is modelled for hemodialyzers. The function of high flux membrane is simulated to observe its role in overall toxin clearance and retaining necessary solutes. In this study, hemodialyzer with a single membrane and multiple membranes are modelled using Finite element method. Toxin clearance is observed by varying different geometric parameters of the hollow fiber and velocity profile of the fluids such as blood and dialysate. Parameters are varied using combinations as per Taguchi algorithm for obtaining optimal results. Dialyzer with multiple membranes showed 20.97% better urea clearance than single membrane. Therefore, this design was further considered for the study of six solutes having different molecular weight ranging from low to high. Results shows that a multi layered membrane have better variance in toxin clearance than single layered hollow fiber membrane though loss of Albumin remains the same.

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T3 - 2020 Advances in Science and Engineering Technology International Conferences, ASET 2020

BT - 2020 Advances in Science and Engineering Technology International Conferences, ASET 2020

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Alex AF, Vinoth R, Dudhe R. A study on hemodialyzer membranes using finite element analysis. In 2020 Advances in Science and Engineering Technology International Conferences, ASET 2020. Institute of Electrical and Electronics Engineers Inc. 2020. 9118354. (2020 Advances in Science and Engineering Technology International Conferences, ASET 2020). doi: 10.1109/ASET48392.2020.9118354

A study on hemodialyzer membranes using finite element analysis

Abstract

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UN SDGs

All Science Journal Classification (ASJC) codes

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