TY - JOUR
T1 - A Visible Light Driven Photoelectrochemical Chloramphenicol Aptasensor Based on a Gold Nanoparticle-Functionalized 3D Flower-like MoS2/TiO2Heterostructure
AU - Zhao, Chunqi
AU - Jing, Tao
AU - Dong, Mengyao
AU - Pan, Duo
AU - Guo, Jiang
AU - Tian, Jingzhi
AU - Wu, Min
AU - Naik, Nithesh
AU - Huang, Mina
AU - Guo, Zhanhu
N1 - Funding Information:
The authors are grateful for the project supported by the National Natural Science Foundation of China (Grant 52172092) and the Qiqihar University Graduate Student Innovative Research Project (YJSCX2019040).
Publisher Copyright:
© 2022 American Chemical Society.
PY - 2022/2/22
Y1 - 2022/2/22
N2 - Developing a photoactive material by combining the characteristics of a wide light response range and effective separation of photogenerated electron-hole pairs remains a huge challenge for the construction of a photoelectrochemical (PEC) sensing platform. Herein, a gold nanoparticle (AuNP)/MoS2/TiO2 composite was prepared through the facile hydrothermal method coupled with an in situ photoreduction technology. Benefiting from both the compositional and structure merits, the composite not only extends the absorption range to visible light but also enhances the photoelectric conversion efficiency by transferring photogenerated electrons into the conduction band of semiconductors from the plasmonic AuNP. Meanwhile, the thiolated aptamers were attached to the surface of AuNP/MoS2/TiO2 composites through the Au-S bonding to construct a visible light driven PEC aptasensor for ultrasensitive detection chloramphenicol (CAP). In the presence of CAP, the aptamers anchored on the surface of the photoactive materials could specifically recognize CAP and interact with it to form a bioaffinity complex with a steric hindrance effect, resulting in the rapid decrease of photocurrent responses. Based on this photocurrent suppression strategy, the constructed PEC aptasensing platform exhibited a high sensitivity with a wide linear range from 5 pM to 100 nM and a low detection limit of 0.5 pM.
AB - Developing a photoactive material by combining the characteristics of a wide light response range and effective separation of photogenerated electron-hole pairs remains a huge challenge for the construction of a photoelectrochemical (PEC) sensing platform. Herein, a gold nanoparticle (AuNP)/MoS2/TiO2 composite was prepared through the facile hydrothermal method coupled with an in situ photoreduction technology. Benefiting from both the compositional and structure merits, the composite not only extends the absorption range to visible light but also enhances the photoelectric conversion efficiency by transferring photogenerated electrons into the conduction band of semiconductors from the plasmonic AuNP. Meanwhile, the thiolated aptamers were attached to the surface of AuNP/MoS2/TiO2 composites through the Au-S bonding to construct a visible light driven PEC aptasensor for ultrasensitive detection chloramphenicol (CAP). In the presence of CAP, the aptamers anchored on the surface of the photoactive materials could specifically recognize CAP and interact with it to form a bioaffinity complex with a steric hindrance effect, resulting in the rapid decrease of photocurrent responses. Based on this photocurrent suppression strategy, the constructed PEC aptasensing platform exhibited a high sensitivity with a wide linear range from 5 pM to 100 nM and a low detection limit of 0.5 pM.
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U2 - 10.1021/acs.langmuir.1c02956
DO - 10.1021/acs.langmuir.1c02956
M3 - Article
AN - SCOPUS:85124885368
SN - 0743-7463
VL - 38
SP - 2276
EP - 2286
JO - Langmuir
JF - Langmuir
IS - 7
ER -