Acute haematologic reaction: Drug or bug?

A. Avinash, Sushil Kiran Kunder, Sharath Madhyastha, Raviraj Acharya, Vinaya Gopalaswamy, Navin Patil, Anurag Pathak, M. N. Vinay

Research output: Contribution to journalArticlepeer-review


β-lactams are known to cause haematologic reactions. Cefoperazone is one such β-lactam that is commonly combined with a β-lactamase inhibitor, sulbactam. A review of the available literature suggests that cefoperazone can cause or precipitate haematologic reactions, including anaemia, leucopenia, thrombocytopenia and hypoprothrombinemia. Similarly, Escherichia coli (E. coli) is a commonly encountered organism associated with urinary tract infections and urosepsis, which can also present in a similar. This case report is a description of an elderly patient who harboured E. coli, and was also given cefoperazone-sulbactam, and later developed haematologic reactions.

Original languageEnglish
Pages (from-to)1884-1886
Number of pages3
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Issue number4
Publication statusPublished - 01-07-2016

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


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