Acute interstitial nephritis related to lansoprazole administration

Jimmy Jose, Kavitha Saravu, Kanav Khera, Beena Jimmy, Barkur Anantha Krishna Shastry

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10 Citations (Scopus)


Acute interstitial nephritis (AIN) is a rare but serious adverse effect reported with proton pump inhibitors (PPIs). Only one report (2 cases) of AIN with lansoprazole is published in literature. A case of lansoprazole induced interstitial nephritis (biopsy supported) was reported in an elderly female patient admitted to the hospital with non specific symptoms after 45 days of treatment with the drug. A recovery was noticed upon withdrawal of the drug and treatment with corticosteroids. We consider this report as a valuable addition to the existing literature on this rare adverse effect with lansoprazole. This potentially serious adverse effect with PPIs including lansoprazole has to be given due consideration, especially taking into account the wide spread use of this group of agents.

Original languageEnglish
Pages (from-to)206-207
Number of pages2
JournalJournal of the Pakistan Medical Association
Issue number4
Publication statusPublished - 04-2008

All Science Journal Classification (ASJC) codes

  • General Medicine


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