TY - GEN
T1 - Algorithms for automatic & non-contact assessment of the cardiovascular system in zebrafish larvae
AU - Krisna, Syam
AU - Chatti, Kiranam
AU - Mestha, Lalit K.
AU - Galigekere, Ramesh R.
PY - 2013/3/8
Y1 - 2013/3/8
N2 - This paper presents several non-contact methods of assessing the state of the cardiovascular system in zebrafish larvae, based on the videos of the animal under a microscope. A new algorithm for automatic detection of the region of interest (ROI) has been developed. Two distinct approaches are used to convert the information in the video to time series. The first involves using the variation in the intensity, and the second involves multichannel time-series based on color information, both within the ROI. The time series are subsequently analyzed for estimating the heart-rate, and also the components of heart rate variability (HRV). The heart-rate estimated from the algorithms is validated by a comparison with the ground-truth obtained by visual-counting. Power spectrum analysis of the beat-to-beat interval sequence exhibited 2 distinct peaks, in the range of [0.15-0.28] and [0.40-0.6], respectively.
AB - This paper presents several non-contact methods of assessing the state of the cardiovascular system in zebrafish larvae, based on the videos of the animal under a microscope. A new algorithm for automatic detection of the region of interest (ROI) has been developed. Two distinct approaches are used to convert the information in the video to time series. The first involves using the variation in the intensity, and the second involves multichannel time-series based on color information, both within the ROI. The time series are subsequently analyzed for estimating the heart-rate, and also the components of heart rate variability (HRV). The heart-rate estimated from the algorithms is validated by a comparison with the ground-truth obtained by visual-counting. Power spectrum analysis of the beat-to-beat interval sequence exhibited 2 distinct peaks, in the range of [0.15-0.28] and [0.40-0.6], respectively.
UR - https://www.scopus.com/pages/publications/84874571494
UR - https://www.scopus.com/pages/publications/84874571494#tab=citedBy
U2 - 10.1109/PHT.2013.6461281
DO - 10.1109/PHT.2013.6461281
M3 - Conference contribution
AN - SCOPUS:84874571494
SN - 9781467327664
T3 - IEEE EMBS Special Topic Conference on Point-of-Care (POC) Healthcare Technologies: Synergy Towards Better Global Healthcare, PHT 2013
SP - 46
EP - 49
BT - IEEE EMBS Special Topic Conference on Point-of-Care (POC) Healthcare Technologies
T2 - 1st IEEE-EMBS Conference on Point-of-Care Healthcare Technologies, PHT 2013
Y2 - 16 January 2013 through 18 January 2013
ER -