Alpha-amylase activity of tannin isolated from Terminalia chebula

Sutapa Mukherjee; Analava Mitra; Satyahari Dey; Goutam Thakur

doi:10.1109/ICSMB.2010.5735421

Alpha-amylase activity of tannin isolated from Terminalia chebula

Sutapa Mukherjee, Analava Mitra, Satyahari Dey, Goutam Thakur

Department of Biomedical Engineering, Manipal Institute of Technology, Manipal

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Citations (Scopus)

Abstract

One important therapeutic approach for the treatment of Type 2 Diabetes Mellitus is by decreasing the postprandial increase of glucose. This is possible by inhibiting certain carbohydrate hydrolyzing enzymes like alpha-amylase. In the present study, the inhibitory effect of tannins isolated from the alcoholic extract of fruits of Terminalia chebula was evaluated for the first time with porcine pancreatic amylase and potato starch as substrate. The result indicated that highest inhibition (52%) was obtained at the concentration of 100g/ml of tannins extracted from the fruits. The result was comparable to that of Acarbose which is a very effective antidiabetic agent.

Original language	English
Title of host publication	International Conference on Systems in Medicine and Biology, ICSMB 2010 - Proceedings
Pages	443-445
Number of pages	3
DOIs	https://doi.org/10.1109/ICSMB.2010.5735421
Publication status	Published - 01-12-2010
Event	International Conference on Systems in Medicine and Biology, ICSMB 2010 - Kharagpur, India Duration: 16-12-2010 → 18-12-2010

Conference

Conference	International Conference on Systems in Medicine and Biology, ICSMB 2010
Country/Territory	India
City	Kharagpur
Period	16-12-10 → 18-12-10

All Science Journal Classification (ASJC) codes

Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1109/ICSMB.2010.5735421

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title = "Alpha-amylase activity of tannin isolated from Terminalia chebula",

abstract = "One important therapeutic approach for the treatment of Type 2 Diabetes Mellitus is by decreasing the postprandial increase of glucose. This is possible by inhibiting certain carbohydrate hydrolyzing enzymes like alpha-amylase. In the present study, the inhibitory effect of tannins isolated from the alcoholic extract of fruits of Terminalia chebula was evaluated for the first time with porcine pancreatic amylase and potato starch as substrate. The result indicated that highest inhibition (52%) was obtained at the concentration of 100g/ml of tannins extracted from the fruits. The result was comparable to that of Acarbose which is a very effective antidiabetic agent.",

author = "Sutapa Mukherjee and Analava Mitra and Satyahari Dey and Goutam Thakur",

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Mukherjee, S, Mitra, A, Dey, S & Thakur, G 2010, Alpha-amylase activity of tannin isolated from Terminalia chebula. in International Conference on Systems in Medicine and Biology, ICSMB 2010 - Proceedings., 5735421, pp. 443-445, International Conference on Systems in Medicine and Biology, ICSMB 2010, Kharagpur, India, 16-12-10. https://doi.org/10.1109/ICSMB.2010.5735421

TY - GEN

T1 - Alpha-amylase activity of tannin isolated from Terminalia chebula

AU - Mukherjee, Sutapa

AU - Mitra, Analava

AU - Dey, Satyahari

AU - Thakur, Goutam

PY - 2010/12/1

Y1 - 2010/12/1

N2 - One important therapeutic approach for the treatment of Type 2 Diabetes Mellitus is by decreasing the postprandial increase of glucose. This is possible by inhibiting certain carbohydrate hydrolyzing enzymes like alpha-amylase. In the present study, the inhibitory effect of tannins isolated from the alcoholic extract of fruits of Terminalia chebula was evaluated for the first time with porcine pancreatic amylase and potato starch as substrate. The result indicated that highest inhibition (52%) was obtained at the concentration of 100g/ml of tannins extracted from the fruits. The result was comparable to that of Acarbose which is a very effective antidiabetic agent.

AB - One important therapeutic approach for the treatment of Type 2 Diabetes Mellitus is by decreasing the postprandial increase of glucose. This is possible by inhibiting certain carbohydrate hydrolyzing enzymes like alpha-amylase. In the present study, the inhibitory effect of tannins isolated from the alcoholic extract of fruits of Terminalia chebula was evaluated for the first time with porcine pancreatic amylase and potato starch as substrate. The result indicated that highest inhibition (52%) was obtained at the concentration of 100g/ml of tannins extracted from the fruits. The result was comparable to that of Acarbose which is a very effective antidiabetic agent.

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BT - International Conference on Systems in Medicine and Biology, ICSMB 2010 - Proceedings

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Alpha-amylase activity of tannin isolated from Terminalia chebula

Abstract

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All Science Journal Classification (ASJC) codes

UN SDGs

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