An unusual case of cutaneous gangrene

Benzathine penicillin is used intramuscularly for the prophylaxis of rheumatic heart disease. We describe here, a child with cutaneous gangrene following an accidental intra-arterial injection of benzathine penicillin in the gluteal area, which was resolved by symptomatic therapy. This is a dangerous but possible adverse effect of this commonly used drug, which can occur due to the practical difficulties which are faced in ruling out intra-arterial injection with this opaque and viscous preparation.