TY - JOUR
T1 - Analysis of the bioactive components in Swietenia macrophylla leaves for their antibacterial and antioxidant capabilities
AU - Borah, Abhinav
AU - Selvaraj, Subbalaxmi
AU - Holla, Sowmya R.
AU - De, Shounak
N1 - Funding Information:
The authors of this study are thankful to the Manipal Institute of Technology, MAHE for providing support towards the conducting of research practices. The contribution and support of the faculty and staff of the Department of Biotechnology, MIT, Department of Chemistry, MIT, and Department of Electronics and Communication Engineering, MIT have been duly acknowledged and appreciated.
Publisher Copyright:
© 2023 Elsevier Ltd
PY - 2023/6
Y1 - 2023/6
N2 - In this study, the extraction of bioactive compounds from Swietenia macrophylla leaves resulted in 50 % (v/v) acetone being the best solvent for extraction of gallic acid, total phenolic compounds, hydrolyzable tannins, and flavonoid content with maximum values of 58.769 μg/mL; 38.153 mgGAE/gdw; 10.586 mg/mL and 64.172 rutin/gdw respectively. FTIR studies indicated the presence of various compounds that have antimicrobial and antibacterial properties. Further, the study of antimicrobial activity showed that the sample acted against Gram-positive bacteria, but not Gram-negative bacteria. On conducting cyclic voltammetry and differential pulse voltammetry, CV showed an anodic peak at 0.2 V with a maximum peak current was at 212 μM; whereas DPV showed various anodic peak potentials at −0.05 V, 0.13 V, 0.23 V, and 0.65 V. TLC was used to qualitatively assess the presence of various bioactive compounds in the plant sample. This study produces bioactive chemicals that are antibacterial and antioxidant.
AB - In this study, the extraction of bioactive compounds from Swietenia macrophylla leaves resulted in 50 % (v/v) acetone being the best solvent for extraction of gallic acid, total phenolic compounds, hydrolyzable tannins, and flavonoid content with maximum values of 58.769 μg/mL; 38.153 mgGAE/gdw; 10.586 mg/mL and 64.172 rutin/gdw respectively. FTIR studies indicated the presence of various compounds that have antimicrobial and antibacterial properties. Further, the study of antimicrobial activity showed that the sample acted against Gram-positive bacteria, but not Gram-negative bacteria. On conducting cyclic voltammetry and differential pulse voltammetry, CV showed an anodic peak at 0.2 V with a maximum peak current was at 212 μM; whereas DPV showed various anodic peak potentials at −0.05 V, 0.13 V, 0.23 V, and 0.65 V. TLC was used to qualitatively assess the presence of various bioactive compounds in the plant sample. This study produces bioactive chemicals that are antibacterial and antioxidant.
UR - https://www.scopus.com/pages/publications/85151239064
UR - https://www.scopus.com/pages/publications/85151239064#tab=citedBy
U2 - 10.1016/j.biteb.2023.101411
DO - 10.1016/j.biteb.2023.101411
M3 - Article
AN - SCOPUS:85151239064
SN - 2589-014X
VL - 22
JO - Bioresource Technology Reports
JF - Bioresource Technology Reports
M1 - 101411
ER -
