Analysis of the bioactive components in Swietenia macrophylla leaves for their antibacterial and antioxidant capabilities

Abhinav Borah; Subbalaxmi Selvaraj; Sowmya R. Holla; Shounak De

doi:10.1016/j.biteb.2023.101411

Analysis of the bioactive components in Swietenia macrophylla leaves for their antibacterial and antioxidant capabilities

Abhinav Borah
, Subbalaxmi Selvaraj^*
, Sowmya R. Holla
, Shounak De

^*Corresponding author for this work

Manipal Institute of Technology, Manipal

Research output: Contribution to journal › Article › peer-review

9 Citations (SciVal)

Abstract

In this study, the extraction of bioactive compounds from Swietenia macrophylla leaves resulted in 50 % (v/v) acetone being the best solvent for extraction of gallic acid, total phenolic compounds, hydrolyzable tannins, and flavonoid content with maximum values of 58.769 μg/mL; 38.153 mgGAE/gdw; 10.586 mg/mL and 64.172 rutin/gdw respectively. FTIR studies indicated the presence of various compounds that have antimicrobial and antibacterial properties. Further, the study of antimicrobial activity showed that the sample acted against Gram-positive bacteria, but not Gram-negative bacteria. On conducting cyclic voltammetry and differential pulse voltammetry, CV showed an anodic peak at 0.2 V with a maximum peak current was at 212 μM; whereas DPV showed various anodic peak potentials at −0.05 V, 0.13 V, 0.23 V, and 0.65 V. TLC was used to qualitatively assess the presence of various bioactive compounds in the plant sample. This study produces bioactive chemicals that are antibacterial and antioxidant.

Original language	English
Article number	101411
Journal	Bioresource Technology Reports
Volume	22
DOIs	https://doi.org/10.1016/j.biteb.2023.101411
Publication status	Published - 06-2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 7 Affordable and Clean Energy

All Science Journal Classification (ASJC) codes

Bioengineering
Environmental Engineering
Renewable Energy, Sustainability and the Environment
Waste Management and Disposal

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10.1016/j.biteb.2023.101411

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title = "Analysis of the bioactive components in Swietenia macrophylla leaves for their antibacterial and antioxidant capabilities",

abstract = "In this study, the extraction of bioactive compounds from Swietenia macrophylla leaves resulted in 50 \% (v/v) acetone being the best solvent for extraction of gallic acid, total phenolic compounds, hydrolyzable tannins, and flavonoid content with maximum values of 58.769 μg/mL; 38.153 mgGAE/gdw; 10.586 mg/mL and 64.172 rutin/gdw respectively. FTIR studies indicated the presence of various compounds that have antimicrobial and antibacterial properties. Further, the study of antimicrobial activity showed that the sample acted against Gram-positive bacteria, but not Gram-negative bacteria. On conducting cyclic voltammetry and differential pulse voltammetry, CV showed an anodic peak at 0.2 V with a maximum peak current was at 212 μM; whereas DPV showed various anodic peak potentials at −0.05 V, 0.13 V, 0.23 V, and 0.65 V. TLC was used to qualitatively assess the presence of various bioactive compounds in the plant sample. This study produces bioactive chemicals that are antibacterial and antioxidant.",

author = "Abhinav Borah and Subbalaxmi Selvaraj and Holla, \{Sowmya R.\} and Shounak De",

note = "Funding Information: The authors of this study are thankful to the Manipal Institute of Technology, MAHE for providing support towards the conducting of research practices. The contribution and support of the faculty and staff of the Department of Biotechnology, MIT, Department of Chemistry, MIT, and Department of Electronics and Communication Engineering, MIT have been duly acknowledged and appreciated. Publisher Copyright: {\textcopyright} 2023 Elsevier Ltd",

year = "2023",

month = jun,

doi = "10.1016/j.biteb.2023.101411",

language = "English",

volume = "22",

journal = "Bioresource Technology Reports",

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AU - Borah, Abhinav

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AU - Holla, Sowmya R.

AU - De, Shounak

N1 - Funding Information: The authors of this study are thankful to the Manipal Institute of Technology, MAHE for providing support towards the conducting of research practices. The contribution and support of the faculty and staff of the Department of Biotechnology, MIT, Department of Chemistry, MIT, and Department of Electronics and Communication Engineering, MIT have been duly acknowledged and appreciated. Publisher Copyright: © 2023 Elsevier Ltd

PY - 2023/6

Y1 - 2023/6

N2 - In this study, the extraction of bioactive compounds from Swietenia macrophylla leaves resulted in 50 % (v/v) acetone being the best solvent for extraction of gallic acid, total phenolic compounds, hydrolyzable tannins, and flavonoid content with maximum values of 58.769 μg/mL; 38.153 mgGAE/gdw; 10.586 mg/mL and 64.172 rutin/gdw respectively. FTIR studies indicated the presence of various compounds that have antimicrobial and antibacterial properties. Further, the study of antimicrobial activity showed that the sample acted against Gram-positive bacteria, but not Gram-negative bacteria. On conducting cyclic voltammetry and differential pulse voltammetry, CV showed an anodic peak at 0.2 V with a maximum peak current was at 212 μM; whereas DPV showed various anodic peak potentials at −0.05 V, 0.13 V, 0.23 V, and 0.65 V. TLC was used to qualitatively assess the presence of various bioactive compounds in the plant sample. This study produces bioactive chemicals that are antibacterial and antioxidant.

AB - In this study, the extraction of bioactive compounds from Swietenia macrophylla leaves resulted in 50 % (v/v) acetone being the best solvent for extraction of gallic acid, total phenolic compounds, hydrolyzable tannins, and flavonoid content with maximum values of 58.769 μg/mL; 38.153 mgGAE/gdw; 10.586 mg/mL and 64.172 rutin/gdw respectively. FTIR studies indicated the presence of various compounds that have antimicrobial and antibacterial properties. Further, the study of antimicrobial activity showed that the sample acted against Gram-positive bacteria, but not Gram-negative bacteria. On conducting cyclic voltammetry and differential pulse voltammetry, CV showed an anodic peak at 0.2 V with a maximum peak current was at 212 μM; whereas DPV showed various anodic peak potentials at −0.05 V, 0.13 V, 0.23 V, and 0.65 V. TLC was used to qualitatively assess the presence of various bioactive compounds in the plant sample. This study produces bioactive chemicals that are antibacterial and antioxidant.

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Analysis of the bioactive components in Swietenia macrophylla leaves for their antibacterial and antioxidant capabilities

Abstract

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All Science Journal Classification (ASJC) codes

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