Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

Ega Durgashivaprasad; Zenab Attari; Jayesh Mudgal; Laxminaryana Kurady Bairy; S Vishnu Prasad; Gopalan Kutty Nampurath

Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

Ega Durgashivaprasad
, Zenab Attari
, Jayesh Mudgal
, Laxminaryana Kurady Bairy
, S Vishnu Prasad
, Gopalan Kutty Nampurath

Research output: Contribution to journal › Article › peer-review

Abstract

A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.

Original language	English
Pages (from-to)	40-44.
Number of pages	5
Journal	Indian Drugs
Volume	52
Issue number	2
Publication status	Published - 2015

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title = "Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives",

abstract = "A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.",

author = "Ega Durgashivaprasad and Zenab Attari and Jayesh Mudgal and Bairy, \{Laxminaryana Kurady\} and \{Vishnu Prasad\}, S and \{Kutty Nampurath\}, Gopalan",

note = "cited By 1",

year = "2015",

language = "English",

volume = "52",

pages = " 40--44.",

journal = "Indian Drugs",

issn = "0019-462X",

publisher = "Indian Drug Manufacturers' Association",

number = "2",

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TY - JOUR

T1 - Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

AU - Durgashivaprasad, Ega

AU - Attari, Zenab

AU - Mudgal, Jayesh

AU - Bairy, Laxminaryana Kurady

AU - Vishnu Prasad, S

AU - Kutty Nampurath, Gopalan

N1 - cited By 1

PY - 2015

Y1 - 2015

N2 - A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.

AB - A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.

M3 - Article

SN - 0019-462X

VL - 52

SP - 40-44.

JO - Indian Drugs

JF - Indian Drugs

IS - 2

ER -

Anti-tubercular activity of synthesized novel 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives

Abstract

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