Antibiotic-associated encephalopathy: A case of cefepime-induced myoclonic encephalopathy

Antibiotics are known to have neurological side-effects, affecting either the central nervous system, peripheral nervous system, or both. Predominant and troublesome central nervous system side-effects are seizures, myoclonus, encephalopathy and peripheral neuropathy. We report a case of myoclonic encephalopathy in a middle-aged diabetic patient with normal renal function, on treatment with cefepime, for Enterobacter cloacae foot infection. Neurological symptoms resolved completely with withdrawal of the drug.