Antimicrobial efficacy of a denovo anti-plaque agent against periodontal pathogens

This research work is carried out to assess the antimicrobial efficacy of an antiplaque agent, Hybnex® against the leading periodontal pathogens which are known to cause periodontal disease. Complete exclusion of these infective microbes and thereby impeding disease progression is the prime focus of periodontal therapy, which is virtually achieved by scaling and root planing. However, for maintenance of such perceptible conditions are carried out by the adjunctive use of antimicrobial agents. A total of fifteen intact human single rooted teeth were inoculated with periodontal pathogens to form a biofilm. The biofilm formed was confirmed using scanning electron microscope (SEM). The specimens were then divided into 3 groups. Group I: specimens were treated with test agent. Group II: specimens were treated with 0.2% Chlorhexidine (CHX) AND Group III: Specimens were treated with deionized water. The results showed comparable antimicrobial activity between test agent (Hybnex®) and CHX (0.2%) when compared to the deionized water, which was statistically significant (p < 0.001).