Antimicrobial resistance refers to the ability of a microbial population to physiologically withstand and overcome the harmful effects of an antimicrobial compound. Concerns regarding the building up of resistance to antimicrobials has surfaced because it diminishes the ability to combat relatively common infections which results in increased healthcare costs as well as increased mortality rate associated with diseases caused by microbes. A major driver of drug resistance is antibiotic misuse which leads to a situation of antibiotic medications turning ineffective. WHO has reported that the failure to address the problem of antibiotic resistance could result in 10 million deaths by 2050.This review discusses the causes for the development of resistance, the resistant bacteria listed by WHO, mechanism of development of resistance and preventive measures to combat drug resistance.
|Number of pages
|Published - 01-08-2017
All Science Journal Classification (ASJC) codes
- Pharmacology, Toxicology and Pharmaceutics(all)