TY - JOUR
T1 - Antioxidant and antibacterial activity of new 3-methylflavones
AU - Jayashree, B. S.
AU - Alam, Afroze
AU - Kumar, D. Vijay
AU - Nayak, Yogendra
N1 - Cited By :3
Export Date: 10 November 2017
Correspondence Address: Jayashree, B. S.; Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal-576104, India; email: [email protected]
References: Li, Y., Fang, H., Xu, W., (2007) Mini Rev. Med. Chem., 7 (7), p. 219; Jung, M., Park, M., Lee, H.C., Kang, Y.H., Kang, E.S., Kim, S.K., (2006) Curr. Med. Chem., 13 (10), p. 1203; Rajakumar, D.V., Rao, M.N., (1995) Free Radic. Res., 22 (4), p. 309; Atta-ur-Rahman, Choudhary, M.I., Thomsen, W.J., (2001) Bioassay Techniques for Drug Development, p. 14. , Harward academic publishers
PY - 2010/1
Y1 - 2010/1
N2 - Synthesis of new 3-methylflavones with various substitution on the ring A and B is being described. They were evaluated for antioxidant and antibacterial activity against Gram positive and Gram negative bacteria. Test compounds such as F-4,9,11,12 and 20 exhibited DPPH radical scavenging activity with IC 50 below 100 μg/ml. The same test compounds exhibited Gram positive bacterial growth inhibition in the range between 50-100% against standard amoxicillin.
AB - Synthesis of new 3-methylflavones with various substitution on the ring A and B is being described. They were evaluated for antioxidant and antibacterial activity against Gram positive and Gram negative bacteria. Test compounds such as F-4,9,11,12 and 20 exhibited DPPH radical scavenging activity with IC 50 below 100 μg/ml. The same test compounds exhibited Gram positive bacterial growth inhibition in the range between 50-100% against standard amoxicillin.
UR - https://www.scopus.com/pages/publications/79958864964
UR - https://www.scopus.com/pages/publications/79958864964#tab=citedBy
M3 - Article
AN - SCOPUS:79958864964
SN - 0971-1627
VL - 19
SP - 237
EP - 240
JO - Indian Journal of Heterocyclic Chemistry
JF - Indian Journal of Heterocyclic Chemistry
IS - 3
ER -