Appendiceal neuroendocrine neoplasms in children and adolescents – Two case reports from a tertiary care center in coastal India

Emerine Selma Edwin, Pooja K. Suresh, Jyoti Kini, Cheryl S. Philipose, Jayateertha Joshi

Research output: Contribution to journalArticlepeer-review

Abstract

Appendiceal neuroendocrine neoplasms (ANENs) are uncommon in children and adolescents and are incidentally diagnosed in 0.3% of appendicectomy specimens. Pediatric ANENs rarely metastasize and have excellent prognosis. We report two cases of ANENs in adolescents who presented clinically and radiologically with features of acute appendicitis for which they underwent appendicectomy. On gross examination, ≤ 2 cm lesion was identified in both the appendix. Microscopic and immunohistochemical analysis clinched the diagnosis of ANENs. Patients were followed up for 18 months and were disease free. This report emphasizes that a possibility of ANEN should be kept as a differential diagnosis even in the pediatric population presenting with acute appendicitis. A routine histopathological examination of all appendicectomy specimens is therefore crucial, as early diagnosis is associated with excellent prognosis.

Original languageEnglish
Pages (from-to)1389-1392
Number of pages4
JournalBiomedicine (India)
Volume42
Issue number6
DOIs
Publication statusPublished - 31-12-2022

All Science Journal Classification (ASJC) codes

  • General Biochemistry,Genetics and Molecular Biology

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