TY - JOUR
T1 - Association of postprandial blood sugar with hypercoagulability in comparison to fasting blood sugars in diabetic and healthy patients
T2 - A cross-sectional study
AU - Kadiyala, Sri Ramulu
AU - Rao, Karthik
AU - Rao, N. R.
AU - Bhat, Ram
AU - Rao, Jayaprakash
AU - Navin, P.
AU - Balaji, O.
N1 - Publisher Copyright:
© 2017 The Authors. Published by Innovare Academic Sciences Pvt Ltd.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Objective: The aim of this study was to find the association of postprandial blood glucose with hypercoagulability in comparison to fasting blood sugars(FBS) in diabetic and healthy patients. Methods: The present study involved a total of 156 patients, of which 78 were taken as cases (diabetics) and other 78 as controls (non-diabetics). Laboratory analysis included prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen assay done along with fasting, and postprandial sugars. Results: Platelets in diabetics and healthy controls were in normal range. Decrease in PT and partial thromboplastin time was noted in diabetics compared to non-diabetic controls. Fibrinogen levels were increased in cases compared to controls. Changes in PT values were more significant with postprandial blood sugar (PPBS) levels when compared to FBS levels, and APTT follows the same pattern with more in PPBS levels and FBS levels in diabetics. PPBS showed elevated fibrinogen when compared to FBS in diabetics as well as non-diabetics. Conclusion: Type 2 diabetes mellitus is a hypercoagulable state as proven by the following results of our study.
AB - Objective: The aim of this study was to find the association of postprandial blood glucose with hypercoagulability in comparison to fasting blood sugars(FBS) in diabetic and healthy patients. Methods: The present study involved a total of 156 patients, of which 78 were taken as cases (diabetics) and other 78 as controls (non-diabetics). Laboratory analysis included prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen assay done along with fasting, and postprandial sugars. Results: Platelets in diabetics and healthy controls were in normal range. Decrease in PT and partial thromboplastin time was noted in diabetics compared to non-diabetic controls. Fibrinogen levels were increased in cases compared to controls. Changes in PT values were more significant with postprandial blood sugar (PPBS) levels when compared to FBS levels, and APTT follows the same pattern with more in PPBS levels and FBS levels in diabetics. PPBS showed elevated fibrinogen when compared to FBS in diabetics as well as non-diabetics. Conclusion: Type 2 diabetes mellitus is a hypercoagulable state as proven by the following results of our study.
UR - http://www.scopus.com/inward/record.url?scp=85021724388&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85021724388&partnerID=8YFLogxK
U2 - 10.22159/ajpcr.2017.v10i7.18806
DO - 10.22159/ajpcr.2017.v10i7.18806
M3 - Article
AN - SCOPUS:85021724388
SN - 0974-2441
VL - 10
SP - 378
EP - 384
JO - Asian Journal of Pharmaceutical and Clinical Research
JF - Asian Journal of Pharmaceutical and Clinical Research
IS - 7
ER -
