TY - JOUR
T1 - Asymmetric oxidation of sulfides catalyzed by (R)-6,6'-dibromo-BINOL derived titanium complex
AU - Maddireddy, Narotham V.
AU - Godbole, Himanshu M.
AU - Singh, Girij P.
AU - Kini, Suvarna G.
AU - Shenoy, Gautham G.
PY - 2020/9/16
Y1 - 2020/9/16
N2 - An efficient asymmetric oxidation of sulfides was achieved using (R)-6,6'-dibromo-BINOL as chiral ligand in combination with Ti(OiPr)4 using 70% aqueous tertiary butyl hydroperoxide as oxidant. The resulting sulfoxides had high enantiopurities and good yields. A range of aryl alkyl and aryl benzyl sulfides were oxidized to the corresponding sulfoxides with 78–95% ee in 72–80% yields.
AB - An efficient asymmetric oxidation of sulfides was achieved using (R)-6,6'-dibromo-BINOL as chiral ligand in combination with Ti(OiPr)4 using 70% aqueous tertiary butyl hydroperoxide as oxidant. The resulting sulfoxides had high enantiopurities and good yields. A range of aryl alkyl and aryl benzyl sulfides were oxidized to the corresponding sulfoxides with 78–95% ee in 72–80% yields.
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U2 - 10.1080/00397911.2020.1786121
DO - 10.1080/00397911.2020.1786121
M3 - Article
AN - SCOPUS:85087632346
SN - 0039-7911
JO - Synthetic Communications
JF - Synthetic Communications
ER -