TY - JOUR
T1 - Baseline risk factors for incidence of blindness in a South Indian population
T2 - The Chennai eye disease incidence study
AU - Vijaya, Lingam
AU - Asokan, Rashima
AU - Panday, Manish
AU - Choudhari, Nikhil S.
AU - Ramesh, Sathyamangalam Ve
AU - Velumuri, Lokapavani
AU - Boddupalli, Sachi Devi
AU - Sunil, Govindan T.
AU - George, Ronnie
PY - 2014/1/1
Y1 - 2014/1/1
N2 - PURPOSE. To report the baseline risk factors and causes for incident blindness.METHODS. Six years after the baseline study, 4419 subjects from the cohort underwent a detailed examination at the base hospital. Incident blindness was defined by World Health Organization criteria as visual acuity of less than 6/120 (3/60) and/or a visual field of less than 108 in the better-seeing eye at the 6-year follow-up, provided that the eye had a visual acuity of better than or equal to 6/120 (3/60) and visual field greater than 108 at baseline. For incident monocular blindness, both eyes should have visual acuity of more than 6/120 (3/60) at baseline and developed visual acuity of less than 6/120 (3/60) in one eye at 6-year follow-up.RESULTS. For incident blindness, 21 participants (0.48%, 95% confidence interval [CI], 0.3–0.7) became blind; significant baseline risk factors were increasing age (P = 0.001), smokeless tobacco use (P < 0.001), and no history of cataract surgery (P = 0.02). Incident monocular blindness was found in 132 participants (3.8%, 95% CI, 3.7–3.8); it was significantly more (P < 0.001) in the rural population (5.4%, 95% CI, 5.4–5.5) than in the urban population (1.9%, 95% CI, 1.8–1.9). Baseline risk factors (P < 0.001) were increasing age and rural residence, and no history of cataract surgery was a protective factor (P = 0.03).CONCLUSIONS. Increasing age was a significant risk factor for blindness and monocular blindness. No history of cataract surgery was a risk factor for blindness and a protective factor for monocular blindness.
AB - PURPOSE. To report the baseline risk factors and causes for incident blindness.METHODS. Six years after the baseline study, 4419 subjects from the cohort underwent a detailed examination at the base hospital. Incident blindness was defined by World Health Organization criteria as visual acuity of less than 6/120 (3/60) and/or a visual field of less than 108 in the better-seeing eye at the 6-year follow-up, provided that the eye had a visual acuity of better than or equal to 6/120 (3/60) and visual field greater than 108 at baseline. For incident monocular blindness, both eyes should have visual acuity of more than 6/120 (3/60) at baseline and developed visual acuity of less than 6/120 (3/60) in one eye at 6-year follow-up.RESULTS. For incident blindness, 21 participants (0.48%, 95% confidence interval [CI], 0.3–0.7) became blind; significant baseline risk factors were increasing age (P = 0.001), smokeless tobacco use (P < 0.001), and no history of cataract surgery (P = 0.02). Incident monocular blindness was found in 132 participants (3.8%, 95% CI, 3.7–3.8); it was significantly more (P < 0.001) in the rural population (5.4%, 95% CI, 5.4–5.5) than in the urban population (1.9%, 95% CI, 1.8–1.9). Baseline risk factors (P < 0.001) were increasing age and rural residence, and no history of cataract surgery was a protective factor (P = 0.03).CONCLUSIONS. Increasing age was a significant risk factor for blindness and monocular blindness. No history of cataract surgery was a risk factor for blindness and a protective factor for monocular blindness.
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U2 - 10.1167/iovs.14-14614
DO - 10.1167/iovs.14-14614
M3 - Article
C2 - 25103268
AN - SCOPUS:84908110236
SN - 0146-0404
VL - 55
SP - 5545
EP - 5550
JO - Investigative Ophthalmology
JF - Investigative Ophthalmology
IS - 9
ER -
