Biocompatible graphitic carbon nitride based fluorescent probe for imaging of breast cancer cell

Meenakshi Talukdar, Raviprasad Kuthethur, Soumyabrata Banik, Nirmal Mazumder, Sanjiban Chakrabarty, Pritam Deb

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Fluorescence imaging materials have gained recent attention compared to existing organic compounds, which have limited lifetime and low stability in biological environments. In this work, a superparamagnetic g-C3N4@FeNi3 heterostructure is developed for sensitive and early cancer detection, showing its potential for fluorescence imaging guidance and monitoring the targeted cancerous cells. Apart from superparamagnetic behaviour, biocompatibility of g-C3N4@FeNi3 heterostructure was evaluated in Human Embryonic Kidney cell line (HEK293) and human breast cancer cell line (MCF-7) which showed no significant change in their viability from 10 µM to 500 µM concentration. Further, confocal fluorescence microscopy in living cancer cells confirmed the potential of this heterostructure in overcoming the drawbacks of commercial fluorophores and their merit of application as labels for optical imaging.

Original languageEnglish
Article number133674
JournalMaterials Letters
Publication statusPublished - 15-02-2023

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering


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