TY - JOUR
T1 - Biological activities and health-promoting effects of Pyracantha genus
T2 - a key approach to the phytochemical's potential
AU - Sharifi-Rad, Javad
AU - Taheri, Yasaman
AU - Ayatollahi, Seyed Abdulmajid
AU - Naderi, Nima
AU - Kumar, Nanjangud Venaktesh Anil
AU - Koirala, Niranjan
AU - Khadka, Sujan
AU - Karazhan, Natallia
AU - Shahinozzaman, Md
AU - Sen, Surjit
AU - Acharya, Krishnendu
AU - Dey, Abhijit
AU - Martorell, Miquel
AU - Martins, Natália
N1 - Publisher Copyright:
Copyright: © 2020 by the C.M.B. Association. All rights reserved.
PY - 2020/6/25
Y1 - 2020/6/25
N2 - Pyracantha spp. are commonly called firethorn, and attract human attention due to their colorful berries. These berries are eaten globally as a traditional remedy for treating different stomach abnormalities, and as a cooking ingredient for folk diets. The present review aims to provide an overview on Pyracantha genus' geographical distribution and botanical description, traditional uses, phytochemical composition, biological activities and safety issues. Several biological activities have been reported to Pyracantha species, namely antioxidant, anti-inflammatory, antimicrobial, larvicidal and cytotoxic properties, most of them attributed to the use of their fruits. Pyracantha species phytochemical composition reveal the presence of interesting bioactive molecules, such as pyracrenic acid and fortuneanosides. The currently reported biological activities to these plants derive from in vitro and in vivo studies, so that clinical trials are needed to confirm these preclinical results. Nonetheless, Pyracantha species can be suggested as a safe herb useful to develop future drug formulations and functional foods.
AB - Pyracantha spp. are commonly called firethorn, and attract human attention due to their colorful berries. These berries are eaten globally as a traditional remedy for treating different stomach abnormalities, and as a cooking ingredient for folk diets. The present review aims to provide an overview on Pyracantha genus' geographical distribution and botanical description, traditional uses, phytochemical composition, biological activities and safety issues. Several biological activities have been reported to Pyracantha species, namely antioxidant, anti-inflammatory, antimicrobial, larvicidal and cytotoxic properties, most of them attributed to the use of their fruits. Pyracantha species phytochemical composition reveal the presence of interesting bioactive molecules, such as pyracrenic acid and fortuneanosides. The currently reported biological activities to these plants derive from in vitro and in vivo studies, so that clinical trials are needed to confirm these preclinical results. Nonetheless, Pyracantha species can be suggested as a safe herb useful to develop future drug formulations and functional foods.
UR - http://www.scopus.com/inward/record.url?scp=85087098147&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85087098147&partnerID=8YFLogxK
U2 - 10.14715/cmb/2020.66.4.4
DO - 10.14715/cmb/2020.66.4.4
M3 - Article
C2 - 32583786
AN - SCOPUS:85087098147
SN - 0145-5680
VL - 66
SP - 20
EP - 27
JO - Cellular and molecular biology (Noisy-le-Grand, France)
JF - Cellular and molecular biology (Noisy-le-Grand, France)
IS - 4
ER -