Brain cancer: Current and new drug delivery systems

The research in the domain of brain cancer has revealed the complexities requiring multidimensional knowledge to combat the challenges posed by it efficiently. The introductory section of this chapter provides a glimpse into the intricate structure of the brain, emphasizing its significance and vulnerability. It also states the categorization of brain cancers based on genetic, oncogenic, and histological features. The global statistics depict the magnitude of the disease, which signifies the importance of addressing the issue on a global scale. The description of available therapies, from conventional approaches like surgery, radiation, and chemotherapy to the emergence of targeted and innovative treatments, showed the evolving landscape of brain cancer treatment. The focus on pharmaceutical, biopharmaceutical, and surgical interventions provided a comprehensive overview of the therapeutics available. Moreover, the exploration of drug delivery systems, particularly the innovative approaches using lipid-based nanoparticles, polymeric nanoparticles, carbon nanotubes, dendrimers, nano-emulsions, and polymer-lipid nano complexes, highlighted the continuous efforts to enhance treatment efficacy. These advancements present promising avenues for overcoming challenges like blood-brain barrier and improving drug delivery precision.