TY - JOUR
T1 - Breast cancer and the heart
T2 - Burden on the chest
AU - Singh, Ajit
AU - Kareem, Hashir
AU - Devasia, Tom
AU - Khera, Kanav
AU - Chauhan, Sheetal
AU - Yeswanth Rao, K.
AU - Ganesh, P.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Breast cancer survivors after successful treatment face various complications in their life. These problems are related to their psycho-social life and/or related to altered body image or may be because of the side effects of breast cancer therapy. Different types of treatment show various hemodynamic/physiological changes on one or more organ/systems. Cardiovascular is the mainly affected system after breast cancer treatment. Radiation-induced heart diseases (RIHD) involve a broad cardiac pathology comprising myocardial fibrosis and cardiomyopathies, pericardial disease, valvular heart diseases, arrhythmias and coronary artery diseases. Chemotherapy induced cardiotoxicity (CIC) affects the morbidity and mortality in breast cancer survivors. Regardless of cancer prognosis; it impacts the quality of life and overall survival with major limitations in life. Conventional diagnostic procedures and biomarkers can be used to detect RIHD and CIC. Cardio-oncology helps in filling the gap between cardiologist and oncologist to reduce the future cardiac risk in survivors.
AB - Breast cancer survivors after successful treatment face various complications in their life. These problems are related to their psycho-social life and/or related to altered body image or may be because of the side effects of breast cancer therapy. Different types of treatment show various hemodynamic/physiological changes on one or more organ/systems. Cardiovascular is the mainly affected system after breast cancer treatment. Radiation-induced heart diseases (RIHD) involve a broad cardiac pathology comprising myocardial fibrosis and cardiomyopathies, pericardial disease, valvular heart diseases, arrhythmias and coronary artery diseases. Chemotherapy induced cardiotoxicity (CIC) affects the morbidity and mortality in breast cancer survivors. Regardless of cancer prognosis; it impacts the quality of life and overall survival with major limitations in life. Conventional diagnostic procedures and biomarkers can be used to detect RIHD and CIC. Cardio-oncology helps in filling the gap between cardiologist and oncologist to reduce the future cardiac risk in survivors.
UR - http://www.scopus.com/inward/record.url?scp=85044763302&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85044763302&partnerID=8YFLogxK
U2 - 10.5530/jcdr.2018.1.1
DO - 10.5530/jcdr.2018.1.1
M3 - Review article
AN - SCOPUS:85044763302
SN - 0975-3583
VL - 9
SP - 1
EP - 4
JO - Journal of Cardiovascular Disease Research
JF - Journal of Cardiovascular Disease Research
IS - 1
ER -
