TY - JOUR
T1 - Calcium pyrophosphate deposition disease causing cervical myelopathy
AU - Bhat, Vaishak Balekkala
AU - Shetty, Daivik T.
AU - Keerthi, Ishwara
AU - Colaco, Sumith Marian
AU - Kolavalli Mohan, Sinchana
AU - Rai, Sharada
N1 - Publisher Copyright:
© BMJ Publishing Group Limited 2025. No commercial re-use. See rights and permissions. Published by BMJ Group.
PY - 2025/7/16
Y1 - 2025/7/16
N2 - Pseudogout, also called calcium pyrophosphate deposition (CPPD), is commonly observed in various joints. In the spine, this deposition is typically found in structures such as the ligamentum flavum, intervertebral disc and posterior longitudinal ligaments. However, the occurrence of calcification or calcific deposits over the dura due to calcium pyrophosphate crystals is a rare phenomenon. It is essential to distinguish dural calcification (DC) from ossification of the ligamentum flavum (OLF) to arrive at the right diagnosis. In this case, an elderly woman presented with rapid-onset cervical myelopathy that was progressive. Radiological assessments, including CT scan and MRI, suggested the presence of DC rather than OLF alone. Routine haematological investigations were within the normal limits. Subsequently, she underwent posterior cervical decompression, stabilisation and fusion. Signs of calcification were observed over the dura, accompanied by greyish-white crystalline deposits. Postoperatively, the patient showed favourable neurological recovery.
AB - Pseudogout, also called calcium pyrophosphate deposition (CPPD), is commonly observed in various joints. In the spine, this deposition is typically found in structures such as the ligamentum flavum, intervertebral disc and posterior longitudinal ligaments. However, the occurrence of calcification or calcific deposits over the dura due to calcium pyrophosphate crystals is a rare phenomenon. It is essential to distinguish dural calcification (DC) from ossification of the ligamentum flavum (OLF) to arrive at the right diagnosis. In this case, an elderly woman presented with rapid-onset cervical myelopathy that was progressive. Radiological assessments, including CT scan and MRI, suggested the presence of DC rather than OLF alone. Routine haematological investigations were within the normal limits. Subsequently, she underwent posterior cervical decompression, stabilisation and fusion. Signs of calcification were observed over the dura, accompanied by greyish-white crystalline deposits. Postoperatively, the patient showed favourable neurological recovery.
UR - https://www.scopus.com/pages/publications/105011086729
UR - https://www.scopus.com/pages/publications/105011086729#tab=citedBy
U2 - 10.1136/bcr-2025-265904
DO - 10.1136/bcr-2025-265904
M3 - Article
AN - SCOPUS:105011086729
SN - 1757-790X
VL - 18
JO - BMJ Case Reports
JF - BMJ Case Reports
IS - 7
M1 - e265904
ER -