TY - JOUR
T1 - Carney complex with PRKAR1A mutation
T2 - A case report
AU - Satyaraddi, Anil
AU - Chapla, Aaron
AU - Shetty, Sahana
AU - Thomas, Nihal
N1 - Publisher Copyright:
© 2016, Australasian Medical Journal Pty Ltd. All rights reserved.
PY - 2016
Y1 - 2016
N2 - Carney complex is a multiple endocrine neoplasia syndrome with various features which include myxomas, endocrine tumours and lentigines lesions. We report a case of Carney complex with components of lentigines, ACTH independent adrenal Cushing’s syndrome (with a paradoxical increase in 24 hour urinary cortisol following the high dose (8mg) dexamethasone suppression test-and is likely to be due to primary pigmented nodular adrenal hyperplasia) positive for a protein kinase A type 1A regulatory subunit (PRKAR1A) gene mutation.
AB - Carney complex is a multiple endocrine neoplasia syndrome with various features which include myxomas, endocrine tumours and lentigines lesions. We report a case of Carney complex with components of lentigines, ACTH independent adrenal Cushing’s syndrome (with a paradoxical increase in 24 hour urinary cortisol following the high dose (8mg) dexamethasone suppression test-and is likely to be due to primary pigmented nodular adrenal hyperplasia) positive for a protein kinase A type 1A regulatory subunit (PRKAR1A) gene mutation.
UR - https://www.scopus.com/pages/publications/84991594187
UR - https://www.scopus.com/inward/citedby.url?scp=84991594187&partnerID=8YFLogxK
U2 - 10.4066/AMJ.2016.2707
DO - 10.4066/AMJ.2016.2707
M3 - Article
AN - SCOPUS:84991594187
SN - 1836-1935
VL - 9
SP - 340
EP - 345
JO - Australasian Medical Journal
JF - Australasian Medical Journal
IS - 9
ER -