TY - JOUR
T1 - Cherubism in siblings
T2 - a case report.
AU - Ongole, Ravikiran
AU - Pillai, Rejeev S.
AU - Pai, Keerthilatha M.
PY - 2003/1/1
Y1 - 2003/1/1
N2 - Cherubism is a non-neoplastic bone disease characterized by clinically evident bilateral, painless enlargements of the jaws that are said to give the patient a cherubic appearance. Cherubism may appear in solitary cases or in many members of the same family, often in multiple generations. On radiography, the lesions exhibit bilateral multilocular radiolucent areas. Histopathologic evaluation reveals proliferating fibrous connective tissue containing numerous multinucleated giant cells. Since the first description of this condition in 1933, almost 200 cases have been reported. We describe cherubism in 2 siblings and briefly review the literature on this subject.
AB - Cherubism is a non-neoplastic bone disease characterized by clinically evident bilateral, painless enlargements of the jaws that are said to give the patient a cherubic appearance. Cherubism may appear in solitary cases or in many members of the same family, often in multiple generations. On radiography, the lesions exhibit bilateral multilocular radiolucent areas. Histopathologic evaluation reveals proliferating fibrous connective tissue containing numerous multinucleated giant cells. Since the first description of this condition in 1933, almost 200 cases have been reported. We describe cherubism in 2 siblings and briefly review the literature on this subject.
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M3 - Review article
C2 - 12622878
AN - SCOPUS:0037364343
SN - 0709-8936
VL - 69
SP - 150
EP - 154
JO - Journal of the Canadian Dental Association
JF - Journal of the Canadian Dental Association
IS - 3
ER -