TY - JOUR
T1 - Childhood onset nephrotic syndrome-a journey through two pregnancies
AU - Bhat, Shashikala K.
AU - Umakanth, Shashikiran
AU - Shah, Krupa
AU - Ashwini, A. P.
AU - Prabhu, Ravindra
N1 - Publisher Copyright:
© 2018, Journal of Clinical and Diagnostic Research. All rights reserved.
PY - 2018/7/1
Y1 - 2018/7/1
N2 - Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema is a rare entity in pregnancy with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach, and pregnancy does not always worsen the existing NS by causing a relapse or disease progression.
AB - Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema is a rare entity in pregnancy with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach, and pregnancy does not always worsen the existing NS by causing a relapse or disease progression.
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U2 - 10.7860/JCDR/2018/36044.11836
DO - 10.7860/JCDR/2018/36044.11836
M3 - Article
AN - SCOPUS:85049518914
SN - 2249-782X
VL - 12
SP - QD08-QD09
JO - Journal of Clinical and Diagnostic Research
JF - Journal of Clinical and Diagnostic Research
IS - 7
ER -