TY - JOUR
T1 - Chronic lithium intoxication
T2 - Varying electrocardiogram manifestations
AU - Maddala, Raja Naga Mahesh
AU - Ashwal, A. J.
AU - Rao, M. Sudhakar
AU - Padmakumar, R.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Lithium is a commonly used drug in psychiatric practice. It is used in the treatment of depression and bipolar disorder. It has a narrow therapeutic index with documented adverse effects even near therapeutic levels. It has myriad of manifestations at toxic levels. The cardiovascular effects range from relatively benign ST-T wave changes to fatal arrhythmias. We describe a case of lithium toxicity which presented as a junctional rhythm and later showed a variety of manifestations such as complete heart block, atrial fibrillation, sinus bradycardia, and finally reverted to sinus rhythm at par with serum lithium levels.
AB - Lithium is a commonly used drug in psychiatric practice. It is used in the treatment of depression and bipolar disorder. It has a narrow therapeutic index with documented adverse effects even near therapeutic levels. It has myriad of manifestations at toxic levels. The cardiovascular effects range from relatively benign ST-T wave changes to fatal arrhythmias. We describe a case of lithium toxicity which presented as a junctional rhythm and later showed a variety of manifestations such as complete heart block, atrial fibrillation, sinus bradycardia, and finally reverted to sinus rhythm at par with serum lithium levels.
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U2 - 10.4103/ijp.IJP_204_16
DO - 10.4103/ijp.IJP_204_16
M3 - Article
C2 - 28458438
AN - SCOPUS:85014532535
SN - 0253-7613
VL - 49
SP - 127
EP - 129
JO - Indian Journal of Pharmacology
JF - Indian Journal of Pharmacology
IS - 1
ER -