TY - JOUR
T1 - Clustering on structured proteins with filtering instances on Bioweka
AU - Vignesh, U.
AU - Parvathi, R.
N1 - Publisher Copyright:
© School of Engineering, Taylor’s University.
PY - 2017/3
Y1 - 2017/3
N2 - This paper presents a synthesis on the analysis of structured proteins through data mining techniques. The protein structure is predicted by using target sequences from BLAST. The predicted protein structure of macropus rufus and structured proteolyzed lysozyme protein are interacted together using mergesets filter for clustering. The selection of a clustering technique for protein clustering is a problem. In order to estimate, performance on three clustering algorithms that are SimpleKMeans, ExpectationMaximization and MakeDensityBasedClusterer are analysed. Carried the simulation experiment on open source data mining tool Bioweka. Comparative analysis with various clustering algorithms illustrates the efficiency of the better clustering algorithm. This method can be applied for the large class of applications such as drug discovery, protein-protein analysis, docking, etc.
AB - This paper presents a synthesis on the analysis of structured proteins through data mining techniques. The protein structure is predicted by using target sequences from BLAST. The predicted protein structure of macropus rufus and structured proteolyzed lysozyme protein are interacted together using mergesets filter for clustering. The selection of a clustering technique for protein clustering is a problem. In order to estimate, performance on three clustering algorithms that are SimpleKMeans, ExpectationMaximization and MakeDensityBasedClusterer are analysed. Carried the simulation experiment on open source data mining tool Bioweka. Comparative analysis with various clustering algorithms illustrates the efficiency of the better clustering algorithm. This method can be applied for the large class of applications such as drug discovery, protein-protein analysis, docking, etc.
UR - https://www.scopus.com/pages/publications/85014659891
UR - https://www.scopus.com/pages/publications/85014659891#tab=citedBy
M3 - Article
AN - SCOPUS:85014659891
SN - 1823-4690
VL - 12
SP - 820
EP - 833
JO - Journal of Engineering Science and Technology
JF - Journal of Engineering Science and Technology
IS - 3
ER -