Communications drug carriers for transdermal preparations of flurbiprofen

U. V. Singh; S. Pandey; N. Udupa

doi:10.3109/03639049409038395

Communications drug carriers for transdermal preparations of flurbiprofen

U. V. Singh, S. Pandey, N. Udupa

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Flurbiprofen was incorporated in different carriers like sodium alginate gel, calcium alginate microspheres, gelatin nanoparticles and complex with betacyclodextrin and incorporated in polyethylene glycol bases. Pharmacodynamic and bioavailability studies were carried out in male rats. It was found that drug incorporated in sodium alginate gel and drug complexed with betacyclodextrin were found to be suitable for designing tranadermal preparations since they resulted in better therapeutic efficacy.

Original language	English
Pages (from-to)	1811-1820
Number of pages	10
Journal	Drug Development and Industrial Pharmacy
Volume	20
Issue number	10
DOIs	https://doi.org/10.3109/03639049409038395
Publication status	Published - 1994

All Science Journal Classification (ASJC) codes

Medicine(all)
Pharmacology
Drug Discovery
Organic Chemistry

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abstract = "Flurbiprofen was incorporated in different carriers like sodium alginate gel, calcium alginate microspheres, gelatin nanoparticles and complex with betacyclodextrin and incorporated in polyethylene glycol bases. Pharmacodynamic and bioavailability studies were carried out in male rats. It was found that drug incorporated in sodium alginate gel and drug complexed with betacyclodextrin were found to be suitable for designing tranadermal preparations since they resulted in better therapeutic efficacy.",

author = "Singh, {U. V.} and S. Pandey and N. Udupa",

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AU - Pandey, S.

AU - Udupa, N.

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AB - Flurbiprofen was incorporated in different carriers like sodium alginate gel, calcium alginate microspheres, gelatin nanoparticles and complex with betacyclodextrin and incorporated in polyethylene glycol bases. Pharmacodynamic and bioavailability studies were carried out in male rats. It was found that drug incorporated in sodium alginate gel and drug complexed with betacyclodextrin were found to be suitable for designing tranadermal preparations since they resulted in better therapeutic efficacy.

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ER -

Communications drug carriers for transdermal preparations of flurbiprofen

Abstract

All Science Journal Classification (ASJC) codes

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