Comparison of yoga and physiotherapy on motor neuropsychiatric symptoms and quality of life in Parkinson's disease

Akash Thunga, Suruliraj Karthikbabu, Venkatesan Prem

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Background: Motor and neuropsychiatric symptoms are the manifestations of Parkinson's disease (PD), leading to poor quality of life of patients. Aim: This study aims to compare the benefits of yoga versus physiotherapy on motor and neuropsychiatric symptoms and health-related quality of life in patients with PD. Materials and Methods: Twenty-four patients with PD, Hoehn and Yahr disease severity rating scale of I-III, score of 3 on a pull test, and walking ability for 10 meters participated in this observer-blinded randomized clinical trial. The yoga group practiced asanas (postures), pranayama (breathing), and meditation. The comparator group underwent physiotherapy. All participants performed 60-minute training sessions a day, with two sessions per week for 12 weeks. The Parkinson's Disease Questionnaire-39 (PDQ-39), Addenbrooke Cognitive Examination (ACE-R), Beck's Depression Inventory (BDI), Unified Parkinson's Disease Rating Scale (UPDRS) motor experiences, and Balance Evaluation System Test (BESTest) were the outcome measurements. Results: On comparing the groups using the Mann-Whitney U test, a statistical significance was observed in the overall quality of life (p = 0.008), emotional well-being (p = 0.008), and stigma (p = 0.048) domains of PDQ-39 and the memory (p = 0.025) and fluency (p = 0.003) domains of ACE-R, which were favorable for yoga. The BDI, UPDRS motor experiences, and BESTest measures were statistically significant (p 0.05) for both the yoga and physiotherapy groups, only on within-group analysis. Conclusion: Psycho-spiritual yoga practice appears to promote emotional well-being and alleviate the stigma attached to PD; therefore, it improves the quality of life of PD patients compared to physical exercises. In addition, it is noted that patients taking antidepressants may experience less depressive symptoms, warranting a multi-Arm parallel-group randomized trial. In conclusion, both yoga and physiotherapy appear to exhibit therapeutic potential in alleviating the motor and neuropsychiatric symptoms of PD and enhancing the balance performance in patients.

Original languageEnglish
Pages (from-to)55-64
Number of pages10
JournalAnnals of Movement Disorders
Issue number1
Publication statusPublished - 01-01-2022

All Science Journal Classification (ASJC) codes

  • Neurology
  • Cognitive Neuroscience
  • Neuroscience (miscellaneous)
  • Surgery
  • Clinical Neurology


Dive into the research topics of 'Comparison of yoga and physiotherapy on motor neuropsychiatric symptoms and quality of life in Parkinson's disease'. Together they form a unique fingerprint.

Cite this