Concomitant polymorphism in 3-acetylcoumarin: Role of weak C-H⋯O and C-H⋯π interactions

Parthapratim Munshi; K. N. Venugopala; B. S. Jayashree; Tayur N. Guru Row

doi:10.1021/cg049948l

Concomitant polymorphism in 3-acetylcoumarin: Role of weak C-H⋯O and C-H⋯π interactions

Parthapratim Munshi
, K. N. Venugopala
, B. S. Jayashree
, Tayur N. Guru Row^*

^*Corresponding author for this work

Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal

Research output: Contribution to journal › Article › peer-review

94 Citations (Scopus)

Abstract

An analysis of structural features associated with polymorphism in 3-acetylcoumarin has been made in terms of morphology, infrared spectroscopy, crystal structure, powder X-ray diffraction, and differential scanning calorimetric measurements. The appearance of concomitant polymorphe is found to depend on the crystallization temperature in the 1:1 chloroform/hexane solvent system. C-H⋯O and C-H⋯π interactions stabilize one form in a head to head configuration, while only C-H⋯O interactions stabilize the other in a head to tail configuration of the molecules in the crystal lattice.

Original language	English
Pages (from-to)	1105-1107
Number of pages	3
Journal	Crystal Growth and Design
Volume	4
Issue number	6
DOIs	https://doi.org/10.1021/cg049948l
Publication status	Published - 01-11-2004

All Science Journal Classification (ASJC) codes

General Chemistry
General Materials Science
Condensed Matter Physics

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10.1021/cg049948l

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abstract = "An analysis of structural features associated with polymorphism in 3-acetylcoumarin has been made in terms of morphology, infrared spectroscopy, crystal structure, powder X-ray diffraction, and differential scanning calorimetric measurements. The appearance of concomitant polymorphe is found to depend on the crystallization temperature in the 1:1 chloroform/hexane solvent system. C-H⋯O and C-H⋯π interactions stabilize one form in a head to head configuration, while only C-H⋯O interactions stabilize the other in a head to tail configuration of the molecules in the crystal lattice.",

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AU - Munshi, Parthapratim

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AU - Jayashree, B. S.

AU - Guru Row, Tayur N.

PY - 2004/11/1

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N2 - An analysis of structural features associated with polymorphism in 3-acetylcoumarin has been made in terms of morphology, infrared spectroscopy, crystal structure, powder X-ray diffraction, and differential scanning calorimetric measurements. The appearance of concomitant polymorphe is found to depend on the crystallization temperature in the 1:1 chloroform/hexane solvent system. C-H⋯O and C-H⋯π interactions stabilize one form in a head to head configuration, while only C-H⋯O interactions stabilize the other in a head to tail configuration of the molecules in the crystal lattice.

AB - An analysis of structural features associated with polymorphism in 3-acetylcoumarin has been made in terms of morphology, infrared spectroscopy, crystal structure, powder X-ray diffraction, and differential scanning calorimetric measurements. The appearance of concomitant polymorphe is found to depend on the crystallization temperature in the 1:1 chloroform/hexane solvent system. C-H⋯O and C-H⋯π interactions stabilize one form in a head to head configuration, while only C-H⋯O interactions stabilize the other in a head to tail configuration of the molecules in the crystal lattice.

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ER -

Concomitant polymorphism in 3-acetylcoumarin: Role of weak C-H⋯O and C-H⋯π interactions

Abstract

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