TY - GEN
T1 - Control of blood glucose concentration in type I diabetic patients
AU - Kamath, Surekha
PY - 2011
Y1 - 2011
N2 - As the "artificial pancreas" becomes closer to reality, automated insulin delivery based on real-time glucose measurements becomes feasible for people with diabetes. This paper employs a new approach to regulate the blood glucose level of type I diabetic patient under an intensive insulin treatment. The closed-loop control scheme incorporates the design of robust H∞ controller to maintain the normoglycemic average of 80 mg/dl. Due to cost and complexity involved in testing the control algorithms to real patients, studies are done using a Type I diabetic patient model. Controller performance is assessed in terms of its ability to reject the effect of meal disturbance and to overcome the variability in the glucoseinsulin dynamics from patient to patient. Computer simulations are used to evaluate the effectiveness of the proposed technique and to show its superiority in controlling hyperglycemia over other existing algorithms.
AB - As the "artificial pancreas" becomes closer to reality, automated insulin delivery based on real-time glucose measurements becomes feasible for people with diabetes. This paper employs a new approach to regulate the blood glucose level of type I diabetic patient under an intensive insulin treatment. The closed-loop control scheme incorporates the design of robust H∞ controller to maintain the normoglycemic average of 80 mg/dl. Due to cost and complexity involved in testing the control algorithms to real patients, studies are done using a Type I diabetic patient model. Controller performance is assessed in terms of its ability to reject the effect of meal disturbance and to overcome the variability in the glucoseinsulin dynamics from patient to patient. Computer simulations are used to evaluate the effectiveness of the proposed technique and to show its superiority in controlling hyperglycemia over other existing algorithms.
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U2 - 10.1109/PACC.2011.5979042
DO - 10.1109/PACC.2011.5979042
M3 - Conference contribution
AN - SCOPUS:80052258521
SN - 9781612847641
T3 - Proceedings of 2011 International Conference on Process Automation, Control and Computing, PACC 2011
BT - Proceedings of 2011 International Conference on Process Automation, Control and Computing, PACC 2011
T2 - 2011 International Conference on Process Automation, Control and Computing, PACC 2011
Y2 - 20 July 2011 through 22 July 2011
ER -
